The importance of nursing homes in the spread of methicillin-resistant Staphylococcus aureus (MRSA) among hospitals

Bruce Lee, Sarah Bartsch, Kim F. Wong, Ashima Singh, Taliser R. Avery, Diane S. Kim, Shawn T. Brown, Courtney R. Murphy, Server Levent Yilmaz, Margaret A. Potter, Susan S. Huang

Research output: Contribution to journalArticle

Abstract

Background: Hospital infection control strategies and programs may not consider control of methicillin-resistant Staphylococcus aureus (MRSA) in nursing homes in a county. Methods: Using our Regional Healthcare Ecosystem Analyst, we augmented our existing agent-based model of all hospitals in Orange County (OC), California, by adding all nursing homes and then simulated MRSA outbreaks in various health care facilities. Results: The addition of nursing homes substantially changed MRSA transmission dynamics throughout the county. The presence of nursing homes substantially potentiated the effects of hospital outbreaks on other hospitals, leading to an average 46.2% (range, 3.3%-156.1%) relative increase above and beyond the impact when only hospitals are included for an outbreak in OC's largest hospital. An outbreak in the largest hospital affected all other hospitals (average 2.1% relative prevalence increase) and the majority (∼90%) of nursing homes (average 3.2% relative increase) after 6 months. An outbreak in the largest nursing home had effects on multiple OC hospitals, increasing MRSA prevalence in directly connected hospitals by an average 0.3% and in hospitals not directly connected through patient transfers by an average 0.1% after 6 months. A nursing home outbreak also had some effect on MRSA prevalence in other nursing homes. Conclusions: Nursing homes, even those not connected by direct patient transfers, may be a vital component of a hospital's infection control strategy. To achieve effective control, a hospital may want to better understand how regional nursing homes and hospitals are connected through both direct and indirect (with intervening stays at home) patient sharing.

Original languageEnglish (US)
Pages (from-to)205-215
Number of pages11
JournalMedical Care
Volume51
Issue number3
DOIs
StatePublished - Mar 2013
Externally publishedYes

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Methicillin-Resistant Staphylococcus aureus
Nursing Homes
Disease Outbreaks
Patient Transfer
Infection Control
Cross Infection
Delivery of Health Care
County Hospitals
Health Facilities
Ecosystem

Keywords

  • hospitals
  • long-term care
  • MRSA
  • nursing homes
  • outbreak

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

The importance of nursing homes in the spread of methicillin-resistant Staphylococcus aureus (MRSA) among hospitals. / Lee, Bruce; Bartsch, Sarah; Wong, Kim F.; Singh, Ashima; Avery, Taliser R.; Kim, Diane S.; Brown, Shawn T.; Murphy, Courtney R.; Yilmaz, Server Levent; Potter, Margaret A.; Huang, Susan S.

In: Medical Care, Vol. 51, No. 3, 03.2013, p. 205-215.

Research output: Contribution to journalArticle

Lee, B, Bartsch, S, Wong, KF, Singh, A, Avery, TR, Kim, DS, Brown, ST, Murphy, CR, Yilmaz, SL, Potter, MA & Huang, SS 2013, 'The importance of nursing homes in the spread of methicillin-resistant Staphylococcus aureus (MRSA) among hospitals', Medical Care, vol. 51, no. 3, pp. 205-215. https://doi.org/10.1097/MLR.0b013e3182836dc2
Lee, Bruce ; Bartsch, Sarah ; Wong, Kim F. ; Singh, Ashima ; Avery, Taliser R. ; Kim, Diane S. ; Brown, Shawn T. ; Murphy, Courtney R. ; Yilmaz, Server Levent ; Potter, Margaret A. ; Huang, Susan S. / The importance of nursing homes in the spread of methicillin-resistant Staphylococcus aureus (MRSA) among hospitals. In: Medical Care. 2013 ; Vol. 51, No. 3. pp. 205-215.
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AB - Background: Hospital infection control strategies and programs may not consider control of methicillin-resistant Staphylococcus aureus (MRSA) in nursing homes in a county. Methods: Using our Regional Healthcare Ecosystem Analyst, we augmented our existing agent-based model of all hospitals in Orange County (OC), California, by adding all nursing homes and then simulated MRSA outbreaks in various health care facilities. Results: The addition of nursing homes substantially changed MRSA transmission dynamics throughout the county. The presence of nursing homes substantially potentiated the effects of hospital outbreaks on other hospitals, leading to an average 46.2% (range, 3.3%-156.1%) relative increase above and beyond the impact when only hospitals are included for an outbreak in OC's largest hospital. An outbreak in the largest hospital affected all other hospitals (average 2.1% relative prevalence increase) and the majority (∼90%) of nursing homes (average 3.2% relative increase) after 6 months. An outbreak in the largest nursing home had effects on multiple OC hospitals, increasing MRSA prevalence in directly connected hospitals by an average 0.3% and in hospitals not directly connected through patient transfers by an average 0.1% after 6 months. A nursing home outbreak also had some effect on MRSA prevalence in other nursing homes. Conclusions: Nursing homes, even those not connected by direct patient transfers, may be a vital component of a hospital's infection control strategy. To achieve effective control, a hospital may want to better understand how regional nursing homes and hospitals are connected through both direct and indirect (with intervening stays at home) patient sharing.

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