The impact of HIV treatment on risk behaviour in developing countries: A systematic review

Caitlin E Kennedy, K. O'Reilly, A. Medley, M. Sweat

Research output: Contribution to journalArticle

Abstract

In developing countries, access to antiretroviral therapy (ART) is improving as HIV treatment becomes a greater priority in the global fight against AIDS. While ART has clearly beneficial clinical effects, increased access to treatment may also affect sexual behaviour. To examine the strength of evidence for the impact of medical treatment for HIV-positive individuals on behavioural outcomes in developing countries, we conducted a comprehensive search of the peer-reviewed literature. Studies were included if they provided clinical treatment to HIV-positive individuals in a developing country, compared behavioural, psychological, social, care, or biological outcomes related to HIV-prevention using a pre/post or multi-arm study design, and were published between January 1990 and January 2006. Only three studies were identified that met the inclusion criteria. All were conducted in Africa, utilized before/after or multi-arm study designs, and relied on self-reported behaviour. In all three studies, a majority of HIV-infected individuals reported being sexually abstinent, and access to ART was not associated with an increase in HIV-related risky sexual behaviours. However, one cross-sectional study found that ART patients were more likely to report STD treatment. The available evidence indicates a significant reduction in risk behaviour associated with ART in developing countries. However, there are few existing studies and the rigor of these studies is weak. More studies are needed to build an evidence base on which to make programmatic and policy decisions.

Original languageEnglish (US)
Pages (from-to)707-720
Number of pages14
JournalAIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV
Volume19
Issue number6
DOIs
StatePublished - Jul 2007

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Risk-Taking
risk behavior
Developing Countries
developing country
HIV
clinical treatment
evidence
Therapeutics
physician's care
cross-sectional study
Sexual Behavior
AIDS
inclusion
Risk Reduction Behavior
Sexually Transmitted Diseases
Acquired Immunodeficiency Syndrome
Cross-Sectional Studies
Psychology

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Health(social science)
  • Health Professions(all)
  • Social Sciences (miscellaneous)

Cite this

The impact of HIV treatment on risk behaviour in developing countries : A systematic review. / Kennedy, Caitlin E; O'Reilly, K.; Medley, A.; Sweat, M.

In: AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV, Vol. 19, No. 6, 07.2007, p. 707-720.

Research output: Contribution to journalArticle

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