The impact of an egg donor's age and her prior fertility on recipient pregnancy outcome

Barbara M. Faber, Suheil J. Muasher, Ramazan Mercan, James P. Toner, Pamela Harnacher

Research output: Contribution to journalArticle

Abstract

Objective: To investigate the effect of donor's age and her prior fertility on recipient pregnancy outcome in our donor egg program. Design: Retrospective cohort analysis. Setting: Large academic infertility center. Patient(s): A total of 568 fresh ETs were analyzed for the effect of the egg donor's age on pregnancy outcome; a subset of these (n = 185) were analyzed for the effect of the egg donor's prior fertility on pregnancy outcome. Intervention(s): Donors were paired with recipients independent of recipient's age and donor's prior fertility status. Main Outcome Measure(s): Recipient clinical pregnancy rates (PRs) and delivery rates for different donor age groups and for nulligravid donors versus donors with proven fertility. Result(s): Donors ≤33 years old were less likely than younger donors to produce clinical pregnancies and deliveries in their recipients (43.5% versus 26.6% and 35.1% versus 22.1%, respectively). However, there was no difference in clinical PRs or delivery rates between nulligravid donors and donors with proven fertility. Conclusion(s): Donors ≤33 years of age could be excluded from egg donation because of the lower pregnancy potential of their eggs. However, lack of proven fertility in a donor seems to have no negative impact on pregnancy potential.

Original languageEnglish (US)
Pages (from-to)370-372
Number of pages3
JournalFertility and sterility
Volume68
Issue number2
DOIs
StatePublished - Aug 1997

Keywords

  • Clinical pregnancy rates
  • Delivery rates
  • Donor age
  • Egg donation
  • Prior fertility

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology

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