The Impact and Management of Fibroids for Fertility. An Evidence-Based Approach

Xiaoxiao Catherine Guo; James H. Segars

doi:10.1016/j.ogc.2012.09.005

The Impact and Management of Fibroids for Fertility. An Evidence-Based Approach

Xiaoxiao Catherine Guo, James H. Segars

Research output: Contribution to journal › Review article › peer-review

50 Scopus citations

Abstract

Fibroids affect 35% to 77% of reproductive-age women. When selecting a treatment plan for symptomatic fibroids, the fibroid location, size, and number must be considered. Myomectomy remains the preferred method for women with fibroid-related infertility who wish to have children or maintain fertility. Currently available medical therapies reduce symptoms in the short term but may involve side effects when used long term. Initial fertility studies are encouraging but trials are needed. Recent medical advances have led to minimally invasive approaches for women with fibroid disease, but there is a strong demand for additional treatment options.

Original language	English (US)
Pages (from-to)	521-533
Number of pages	13
Journal	Obstetrics and Gynecology Clinics of North America
Volume	39
Issue number	4
DOIs	https://doi.org/10.1016/j.ogc.2012.09.005
State	Published - Dec 2012
Externally published	Yes

Keywords

Assisted reproductive technology (ART)
Hysteroscopy
Infertility
Leiomyoma
Magnetic resonance-guided focused ultrasound (MRgFUS)
Minimally invasive gynecologic surgeries
Myomectomy
Uterine artery embolization (UAE)

ASJC Scopus subject areas

Obstetrics and Gynecology

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10.1016/j.ogc.2012.09.005

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title = "The Impact and Management of Fibroids for Fertility. An Evidence-Based Approach",

abstract = "Fibroids affect 35% to 77% of reproductive-age women. When selecting a treatment plan for symptomatic fibroids, the fibroid location, size, and number must be considered. Myomectomy remains the preferred method for women with fibroid-related infertility who wish to have children or maintain fertility. Currently available medical therapies reduce symptoms in the short term but may involve side effects when used long term. Initial fertility studies are encouraging but trials are needed. Recent medical advances have led to minimally invasive approaches for women with fibroid disease, but there is a strong demand for additional treatment options.",

keywords = "Assisted reproductive technology (ART), Hysteroscopy, Infertility, Leiomyoma, Magnetic resonance-guided focused ultrasound (MRgFUS), Minimally invasive gynecologic surgeries, Myomectomy, Uterine artery embolization (UAE)",

author = "Guo, {Xiaoxiao Catherine} and Segars, {James H.}",

note = "Funding Information: This research was supported, in part, by the Intramural Research Program in Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health. The authors would like to thank Alan DeCherney, MD, for his mentorship and guidance and the National Institutes of Health , NICHD , PRAE , and IRTA program for their support.",

year = "2012",

month = dec,

doi = "10.1016/j.ogc.2012.09.005",

language = "English (US)",

volume = "39",

pages = "521--533",

journal = "Obstetrics and Gynecology Clinics of North America",

issn = "0889-8545",

publisher = "W.B. Saunders Ltd",

number = "4",

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T1 - The Impact and Management of Fibroids for Fertility. An Evidence-Based Approach

AU - Guo, Xiaoxiao Catherine

AU - Segars, James H.

N1 - Funding Information: This research was supported, in part, by the Intramural Research Program in Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health. The authors would like to thank Alan DeCherney, MD, for his mentorship and guidance and the National Institutes of Health , NICHD , PRAE , and IRTA program for their support.

PY - 2012/12

Y1 - 2012/12

N2 - Fibroids affect 35% to 77% of reproductive-age women. When selecting a treatment plan for symptomatic fibroids, the fibroid location, size, and number must be considered. Myomectomy remains the preferred method for women with fibroid-related infertility who wish to have children or maintain fertility. Currently available medical therapies reduce symptoms in the short term but may involve side effects when used long term. Initial fertility studies are encouraging but trials are needed. Recent medical advances have led to minimally invasive approaches for women with fibroid disease, but there is a strong demand for additional treatment options.

AB - Fibroids affect 35% to 77% of reproductive-age women. When selecting a treatment plan for symptomatic fibroids, the fibroid location, size, and number must be considered. Myomectomy remains the preferred method for women with fibroid-related infertility who wish to have children or maintain fertility. Currently available medical therapies reduce symptoms in the short term but may involve side effects when used long term. Initial fertility studies are encouraging but trials are needed. Recent medical advances have led to minimally invasive approaches for women with fibroid disease, but there is a strong demand for additional treatment options.

KW - Assisted reproductive technology (ART)

KW - Hysteroscopy

KW - Infertility

KW - Leiomyoma

KW - Magnetic resonance-guided focused ultrasound (MRgFUS)

KW - Minimally invasive gynecologic surgeries

KW - Myomectomy

KW - Uterine artery embolization (UAE)

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U2 - 10.1016/j.ogc.2012.09.005

DO - 10.1016/j.ogc.2012.09.005

M3 - Review article

C2 - 23182558

AN - SCOPUS:84870210338

SN - 0889-8545

VL - 39

SP - 521

EP - 533

JO - Obstetrics and Gynecology Clinics of North America

JF - Obstetrics and Gynecology Clinics of North America

IS - 4

ER -

The Impact and Management of Fibroids for Fertility. An Evidence-Based Approach

Abstract

Keywords

ASJC Scopus subject areas

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