The human calcitonin gene is located on the short ARM of chromosome 11

Donna Przepiorka; Stephen B. Baylin; O. Wesley McBride; Joseph R. Testa; Andree de Bustros; Barry D. Nelkin

doi:10.1016/0006-291X(84)91281-6

The human calcitonin gene is located on the short ARM of chromosome 11

Donna Przepiorka, Stephen B. Baylin, O. Wesley McBride, Joseph R. Testa, Andree de Bustros, Barry D. Nelkin

School of Medicine

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

By molecular hybridization of human calcitonin cDNA probes to DNA from human-rodent hybrid cells containing identified human chromosomes, we have mapped the human calcitonin gene to the short arm of chromosome 11. This location has been confirmed by in situ hybridization, which further localized the calcitonin gene to region 11p13-15. The significance of this region regarding gene linkage and possible markers for inherited cancers is discussed.

Original language	English (US)
Pages (from-to)	493-499
Number of pages	7
Journal	Biochemical and Biophysical Research Communications
Volume	120
Issue number	2
DOIs	https://doi.org/10.1016/0006-291X(84)91281-6
State	Published - Apr 30 1984

ASJC Scopus subject areas

Biophysics
Biochemistry
Molecular Biology
Cell Biology

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10.1016/0006-291X(84)91281-6

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abstract = "By molecular hybridization of human calcitonin cDNA probes to DNA from human-rodent hybrid cells containing identified human chromosomes, we have mapped the human calcitonin gene to the short arm of chromosome 11. This location has been confirmed by in situ hybridization, which further localized the calcitonin gene to region 11p13-15. The significance of this region regarding gene linkage and possible markers for inherited cancers is discussed.",

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AU - Przepiorka, Donna

AU - Baylin, Stephen B.

AU - McBride, O. Wesley

AU - Testa, Joseph R.

AU - de Bustros, Andree

AU - Nelkin, Barry D.

PY - 1984/4/30

Y1 - 1984/4/30

N2 - By molecular hybridization of human calcitonin cDNA probes to DNA from human-rodent hybrid cells containing identified human chromosomes, we have mapped the human calcitonin gene to the short arm of chromosome 11. This location has been confirmed by in situ hybridization, which further localized the calcitonin gene to region 11p13-15. The significance of this region regarding gene linkage and possible markers for inherited cancers is discussed.

AB - By molecular hybridization of human calcitonin cDNA probes to DNA from human-rodent hybrid cells containing identified human chromosomes, we have mapped the human calcitonin gene to the short arm of chromosome 11. This location has been confirmed by in situ hybridization, which further localized the calcitonin gene to region 11p13-15. The significance of this region regarding gene linkage and possible markers for inherited cancers is discussed.

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The human calcitonin gene is located on the short ARM of chromosome 11

Abstract

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