The histopathology of acute renal failure

L. C. Racusen

Research output: Contribution to journalReview articlepeer-review


The morphologic and immunohistologic features in acute renal failure (ARF) are discussed in this article. The focus is on tubular epithelial cell injury, the central pathologic finding in the majority of cases of ARF. Tubular damage may be due to sublethal or lethal cell injury. Cell necrosis, including classic coagulative necrosis and apoptosis, manifestations of sublethal injury, and tubular cell exfoliation are described in detail. Pathologic findings in native kidneys are described.

Original languageEnglish (US)
Pages (from-to)662-668
Number of pages7
JournalNew Horizons: Science and Practice of Acute Medicine
Issue number4
StatePublished - 1995


  • acute renal failure
  • apoptosis
  • epithelium
  • exfoliation
  • injury
  • ischemia
  • kidney
  • necrosis
  • toxins
  • tubule

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine


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