The haemophilia A mutation search test and resource site, home page of the factor VIII mutation database: HAMSTeRS

A. I. Wacey, G. Kemball-Cook, Haig Kazazian, S. E. Antonarakis, R. Schwaab, P. Lindley, E. G D Tuddenham

Research output: Contribution to journalArticle

Abstract

In order to facilitate easy access to and aid understanding of the causes of haemophilia A at the molecular level we have constructed HAMSTeRS, the third release of the factor VIII mutation database and the first release of this database that may be accessed and interrogated over the internet through a World Wide Web browser. The database also presents a review of the structure and function of factor VIII and the molecular genetics of haemophilia A, a real time update of the biostatistics of each parameter in the database, a molecular model of the A1, A2 and A3 domains of the factor VIII protein (based on the crystal structure of caeruloplasmin) and a bulletin board for discussion of issues in the molecular biology of factor VIII.

Original languageEnglish (US)
Pages (from-to)100-102
Number of pages3
JournalNucleic Acids Research
Volume24
Issue number1
DOIs
StatePublished - 1996

Fingerprint

Factor VIII
Hemophilia A
Databases
Mutation
Internet
Molecular Biology
Web Browser
Biostatistics
Ceruloplasmin
Molecular Models
varespladib methyl
Proteins

ASJC Scopus subject areas

  • Genetics

Cite this

Wacey, A. I., Kemball-Cook, G., Kazazian, H., Antonarakis, S. E., Schwaab, R., Lindley, P., & Tuddenham, E. G. D. (1996). The haemophilia A mutation search test and resource site, home page of the factor VIII mutation database: HAMSTeRS. Nucleic Acids Research, 24(1), 100-102. https://doi.org/10.1093/nar/24.1.100

The haemophilia A mutation search test and resource site, home page of the factor VIII mutation database : HAMSTeRS. / Wacey, A. I.; Kemball-Cook, G.; Kazazian, Haig; Antonarakis, S. E.; Schwaab, R.; Lindley, P.; Tuddenham, E. G D.

In: Nucleic Acids Research, Vol. 24, No. 1, 1996, p. 100-102.

Research output: Contribution to journalArticle

Wacey, AI, Kemball-Cook, G, Kazazian, H, Antonarakis, SE, Schwaab, R, Lindley, P & Tuddenham, EGD 1996, 'The haemophilia A mutation search test and resource site, home page of the factor VIII mutation database: HAMSTeRS', Nucleic Acids Research, vol. 24, no. 1, pp. 100-102. https://doi.org/10.1093/nar/24.1.100
Wacey, A. I. ; Kemball-Cook, G. ; Kazazian, Haig ; Antonarakis, S. E. ; Schwaab, R. ; Lindley, P. ; Tuddenham, E. G D. / The haemophilia A mutation search test and resource site, home page of the factor VIII mutation database : HAMSTeRS. In: Nucleic Acids Research. 1996 ; Vol. 24, No. 1. pp. 100-102.
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