The Gut Microbiome in Pancreatic Disease

Venkata S. Akshintala, Rupjyoti Talukdar, Vikesh K. Singh, Michael Goggins

Research output: Contribution to journalReview articlepeer-review


The gut microbiome increasingly is recognized for its role in human health and disease. Initial evidence has indicated that gut microbial dysbiosis is associated with several pancreatic diseases. Although it is not known if these associations are causative, gut dysbiosis is hypothesized to mediate chronic proinflammatory changes in the pancreas. Further mechanistic and epidemiologic studies of the microbiome are needed. Ultimately, targeted modulation of the microbiota could have therapeutic value.

Original languageEnglish (US)
Pages (from-to)290-295
Number of pages6
JournalClinical Gastroenterology and Hepatology
Issue number2
StatePublished - Jan 2019


  • Dysbiosis
  • Intratumoral Bacteria
  • Microbiome
  • Pancreatic Cancer
  • Pancreatitis
  • Probiotics

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology


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