TY - JOUR
T1 - The GRID-HAMD
T2 - Standardization of the Hamilton depression rating scale
AU - Williams, Janet B.W.
AU - Kobak, Kenneth A.
AU - Bech, Per
AU - Engelhardt, Nina
AU - Evans, Ken
AU - Lipsitz, Joshua
AU - Olin, Jason
AU - Pearson, Jay
AU - Kalali, Amir
PY - 2008/5/1
Y1 - 2008/5/1
N2 - This report describes the GRID-Hamilton Depression Rating Scale (GRID-HAMD), an improved version of the Hamilton Depression Rating Scale that was developed through a broad-based international consensus process. The GRID-HAMD separates the frequency of the symptom from its intensity for most items, refines several problematic anchors, and integrates both a structured interview guide and consensus-derived conventions for all items. Usability was established in a small three-site sample of convenience, evaluating 29 outpatients, with most evaluators finding the scale easy to use. Test-retest (4-week) and interrater reliability were established in 34 adult outpatients with major depressive disorder, as part of an ongoing clinical trial. In a separate study, interrater reliability was found to be superior to the Guy version of the HAMD, and as good as the Structured Interview Guide for the Hamilton Depression Rating Scale (SIGH-D), across 30 interview pairs. Finally, using the SIGH-D as the criterion standard, the GRID-HAMD demonstrated high concurrent validity. Overall, these data suggest that the GRID-HAMD is an improvement over the original Guy version as well as the SIGH-D in its incorporation of innovative features and preservation of high reliability and validity.
AB - This report describes the GRID-Hamilton Depression Rating Scale (GRID-HAMD), an improved version of the Hamilton Depression Rating Scale that was developed through a broad-based international consensus process. The GRID-HAMD separates the frequency of the symptom from its intensity for most items, refines several problematic anchors, and integrates both a structured interview guide and consensus-derived conventions for all items. Usability was established in a small three-site sample of convenience, evaluating 29 outpatients, with most evaluators finding the scale easy to use. Test-retest (4-week) and interrater reliability were established in 34 adult outpatients with major depressive disorder, as part of an ongoing clinical trial. In a separate study, interrater reliability was found to be superior to the Guy version of the HAMD, and as good as the Structured Interview Guide for the Hamilton Depression Rating Scale (SIGH-D), across 30 interview pairs. Finally, using the SIGH-D as the criterion standard, the GRID-HAMD demonstrated high concurrent validity. Overall, these data suggest that the GRID-HAMD is an improvement over the original Guy version as well as the SIGH-D in its incorporation of innovative features and preservation of high reliability and validity.
KW - Clinical trials
KW - Depressive disorder
KW - Psychiatric Status Rating Scales
KW - Treatment outcome
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U2 - 10.1097/YIC.0b013e3282f948f5
DO - 10.1097/YIC.0b013e3282f948f5
M3 - Article
C2 - 18408526
AN - SCOPUS:42149190590
SN - 0268-1315
VL - 23
SP - 120
EP - 129
JO - International Clinical Psychopharmacology
JF - International Clinical Psychopharmacology
IS - 3
ER -