Le fardeau mondial du choléra

Translated title of the contribution: The global burden of cholera

Mohammad Ali, Anna Lena Lopez, Young Ae You, Young Eun Kim, Binod Sah, Brian Maskery, John Clemens

Research output: Contribution to journalReview articlepeer-review


Objective To estimate the global burden of cholera using population-based incidence data and reports. Methods Countries with a recent history of cholera were classifed as endemic or non-endemic, depending on whether they had reported cholera cases in at least three of the fve most recent years. The percentages of the population in each country that lacked access to improved sanitation were used to compute the populations at risk for cholera, and incidence rates from published studies were applied to groups of countries to estimate the annual number of cholera cases in endemic countries. The estimates of cholera cases in non-endemic countries were based on the average numbers of cases reported from 2000 to 2008. Literature-based estimates of cholera case-fatality rates (CFRs) were used to compute the variance-weighted average cholera CFRs for estimating the number of cholera deaths. Findings About 1.4 billion people are at risk for cholera in endemic countries. An estimated 2.8 million cholera cas s occur annually in such countries (uncertainty range: 1.4-4.3) and an estimated 87 000 cholera cases occur in non-endemic countries. The incidence is estimatedto be greatest in children less than 5 years of age. Every year about 91 000 people (uncertainty range: 28 000 to 142 000) die of cholera in endemic countries and 2500 people die of the disease in non-endemic countries. Conclusion The global burden of cholera, as determined through a systematic review with clearly stated assumptions, is high. The fndings of this study provide a contemporary basis for planning public health interventions to control cholera.

Translated title of the contributionThe global burden of cholera
Original languageFrench
Pages (from-to)209-218
Number of pages10
JournalBulletin of the World Health Organization
Issue number3
StatePublished - Mar 2012
Externally publishedYes

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health


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