The genome of non-O1 Vibrio cholerae NRT36S demonstrates the presence of pathogenic mechanisms that are distinct from those of O1 Vibrio cholerae

Yuansha Chen, Judith A. Johnson, Gordon D. Pusch, J. Glenn Morris, O. Colin Stine

Research output: Contribution to journalArticlepeer-review

Abstract

Vibrio cholerae NRT36S is a non-cholera toxin-producing, non-O1 strain that causes diarrhea in volunteers. The genome of NRT36S was sequenced to create a draft containing 174 contigs plus the superintegron region. Our analysis of the draft genome revealed several putative toxin genes and colonization factors. Besides confirming the existence of nonagglutinable heat-stable toxin, we also identified the genes for a type three secretion system, a putative exotoxin, two different RTX toxins, and four pilus systems.

Original languageEnglish (US)
Pages (from-to)2645-2647
Number of pages3
JournalInfection and Immunity
Volume75
Issue number5
DOIs
StatePublished - May 2007
Externally publishedYes

ASJC Scopus subject areas

  • Immunology

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