The genetics and complexity of allergy and asthma

Kathleen C. Barnes, David G. Marsh

Research output: Contribution to journalArticle


Why do common diseases such as allergy and asthma have complex patterns of inheritance while other, relatively uncommon diseases approximate simple Mendelian traits? There is good evidence that the dysfunctioning of highly involved, interactive genetic networks is implicated in most complex diseases. Here, Kathleen Barnes and David Marsh review recent studies of asthma, which provide a good model for illustrating this point.

Original languageEnglish (US)
Pages (from-to)325-332
Number of pages8
JournalImmunology Today
Issue number7
StatePublished - Jul 1 1998

ASJC Scopus subject areas

  • Immunology

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