The genetics and complexity of allergy and asthma

Kathleen C. Barnes; David G. Marsh

doi:10.1016/S0167-5699(97)01241-3

The genetics and complexity of allergy and asthma

Kathleen C. Barnes, David G. Marsh

School of Medicine

Research output: Contribution to journal › Article › peer-review

100 Scopus citations

Abstract

Why do common diseases such as allergy and asthma have complex patterns of inheritance while other, relatively uncommon diseases approximate simple Mendelian traits? There is good evidence that the dysfunctioning of highly involved, interactive genetic networks is implicated in most complex diseases. Here, Kathleen Barnes and David Marsh review recent studies of asthma, which provide a good model for illustrating this point.

Original language	English (US)
Pages (from-to)	325-332
Number of pages	8
Journal	Immunology Today
Volume	19
Issue number	7
DOIs	https://doi.org/10.1016/S0167-5699(97)01241-3
State	Published - Jul 1 1998

ASJC Scopus subject areas

Immunology

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10.1016/S0167-5699(97)01241-3

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abstract = "Why do common diseases such as allergy and asthma have complex patterns of inheritance while other, relatively uncommon diseases approximate simple Mendelian traits? There is good evidence that the dysfunctioning of highly involved, interactive genetic networks is implicated in most complex diseases. Here, Kathleen Barnes and David Marsh review recent studies of asthma, which provide a good model for illustrating this point.",

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The genetics and complexity of allergy and asthma

Abstract

ASJC Scopus subject areas

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