The genetic diversity of influenza A viruses in wild birds in Peru

Martha I. Nelson, Simon Pollett, Bruno Ghersi, Maria Silva, Mark P. Simons, Eliana Icochea, Armandoe Gonzalez, Karen Segovia, Matthew R. Kasper, Joel M. Montgomery, Daniel G. Bausch

Research output: Contribution to journalArticle

Abstract

Our understanding of the global ecology of avian influenza A viruses (AIVs) is impeded by historically low levels of viral surveillance in Latin America. Through sampling and wholegenome sequencing of 31 AIVs from wild birds in Peru, we identified 10 HA subtypes (H1- H4, H6-H7, H10-H13) and 8 NA subtypes (N1-N3, N5-N9). The majority of Peruvian AIVs were closely related to AIVs found in North America. However, unusual reassortants, including a H13 virus containing a PA segment related to extremely divergent Argentinian viruses, suggest that substantial AIV diversity circulates undetected throughout South America.

Original languageEnglish (US)
Article numbere0146059
JournalPLoS One
Volume11
Issue number1
DOIs
StatePublished - Jan 1 2016
Externally publishedYes

Fingerprint

Peru
Influenza in Birds
Influenza A virus
Birds
wild birds
Viruses
genetic variation
viruses
Latin America
South America
North America
Ecology
ecology
monitoring
Sampling
sampling

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

Cite this

Nelson, M. I., Pollett, S., Ghersi, B., Silva, M., Simons, M. P., Icochea, E., ... Bausch, D. G. (2016). The genetic diversity of influenza A viruses in wild birds in Peru. PLoS One, 11(1), [e0146059]. https://doi.org/10.1371/journal.pone.0146059

The genetic diversity of influenza A viruses in wild birds in Peru. / Nelson, Martha I.; Pollett, Simon; Ghersi, Bruno; Silva, Maria; Simons, Mark P.; Icochea, Eliana; Gonzalez, Armandoe; Segovia, Karen; Kasper, Matthew R.; Montgomery, Joel M.; Bausch, Daniel G.

In: PLoS One, Vol. 11, No. 1, e0146059, 01.01.2016.

Research output: Contribution to journalArticle

Nelson, MI, Pollett, S, Ghersi, B, Silva, M, Simons, MP, Icochea, E, Gonzalez, A, Segovia, K, Kasper, MR, Montgomery, JM & Bausch, DG 2016, 'The genetic diversity of influenza A viruses in wild birds in Peru', PLoS One, vol. 11, no. 1, e0146059. https://doi.org/10.1371/journal.pone.0146059
Nelson MI, Pollett S, Ghersi B, Silva M, Simons MP, Icochea E et al. The genetic diversity of influenza A viruses in wild birds in Peru. PLoS One. 2016 Jan 1;11(1). e0146059. https://doi.org/10.1371/journal.pone.0146059
Nelson, Martha I. ; Pollett, Simon ; Ghersi, Bruno ; Silva, Maria ; Simons, Mark P. ; Icochea, Eliana ; Gonzalez, Armandoe ; Segovia, Karen ; Kasper, Matthew R. ; Montgomery, Joel M. ; Bausch, Daniel G. / The genetic diversity of influenza A viruses in wild birds in Peru. In: PLoS One. 2016 ; Vol. 11, No. 1.
@article{3e80b5a83ef34c359242764b55640246,
title = "The genetic diversity of influenza A viruses in wild birds in Peru",
abstract = "Our understanding of the global ecology of avian influenza A viruses (AIVs) is impeded by historically low levels of viral surveillance in Latin America. Through sampling and wholegenome sequencing of 31 AIVs from wild birds in Peru, we identified 10 HA subtypes (H1- H4, H6-H7, H10-H13) and 8 NA subtypes (N1-N3, N5-N9). The majority of Peruvian AIVs were closely related to AIVs found in North America. However, unusual reassortants, including a H13 virus containing a PA segment related to extremely divergent Argentinian viruses, suggest that substantial AIV diversity circulates undetected throughout South America.",
author = "Nelson, {Martha I.} and Simon Pollett and Bruno Ghersi and Maria Silva and Simons, {Mark P.} and Eliana Icochea and Armandoe Gonzalez and Karen Segovia and Kasper, {Matthew R.} and Montgomery, {Joel M.} and Bausch, {Daniel G.}",
year = "2016",
month = "1",
day = "1",
doi = "10.1371/journal.pone.0146059",
language = "English (US)",
volume = "11",
journal = "PLoS One",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "1",

}

TY - JOUR

T1 - The genetic diversity of influenza A viruses in wild birds in Peru

AU - Nelson, Martha I.

AU - Pollett, Simon

AU - Ghersi, Bruno

AU - Silva, Maria

AU - Simons, Mark P.

AU - Icochea, Eliana

AU - Gonzalez, Armandoe

AU - Segovia, Karen

AU - Kasper, Matthew R.

AU - Montgomery, Joel M.

AU - Bausch, Daniel G.

PY - 2016/1/1

Y1 - 2016/1/1

N2 - Our understanding of the global ecology of avian influenza A viruses (AIVs) is impeded by historically low levels of viral surveillance in Latin America. Through sampling and wholegenome sequencing of 31 AIVs from wild birds in Peru, we identified 10 HA subtypes (H1- H4, H6-H7, H10-H13) and 8 NA subtypes (N1-N3, N5-N9). The majority of Peruvian AIVs were closely related to AIVs found in North America. However, unusual reassortants, including a H13 virus containing a PA segment related to extremely divergent Argentinian viruses, suggest that substantial AIV diversity circulates undetected throughout South America.

AB - Our understanding of the global ecology of avian influenza A viruses (AIVs) is impeded by historically low levels of viral surveillance in Latin America. Through sampling and wholegenome sequencing of 31 AIVs from wild birds in Peru, we identified 10 HA subtypes (H1- H4, H6-H7, H10-H13) and 8 NA subtypes (N1-N3, N5-N9). The majority of Peruvian AIVs were closely related to AIVs found in North America. However, unusual reassortants, including a H13 virus containing a PA segment related to extremely divergent Argentinian viruses, suggest that substantial AIV diversity circulates undetected throughout South America.

UR - http://www.scopus.com/inward/record.url?scp=84958567760&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84958567760&partnerID=8YFLogxK

U2 - 10.1371/journal.pone.0146059

DO - 10.1371/journal.pone.0146059

M3 - Article

C2 - 26784331

AN - SCOPUS:84958567760

VL - 11

JO - PLoS One

JF - PLoS One

SN - 1932-6203

IS - 1

M1 - e0146059

ER -