The future of HIV Organ Policy Equity Act is now: The state of HIV+ to HIV+ kidney transplantation in the United States

Brian J. Boyarsky, Mary Grace Bowring, Ashton A. Shaffer, Dorry Segev, Christine Durand

Research output: Contribution to journalReview articlepeer-review

Abstract

Purpose of reviewWe report the current state of HIV+ to HIV+ kidney transplantation in the United States and remaining challenges in implementing this practice nationally.Recent findingsThe HIV Organ Policy Equity (HOPE) Act, which was the first step in unlocking the potential of HIV+ organ donors, mandates clinical research on HIV+ to HIV+ transplantation. As of March 2019, there have been 57 HOPE donors, including both true and false positive HOPE donors resulting in more than 120 transplants.SummaryThe HOPE Act, signed in 2013, reversed the federal ban on the transplantation of organs from HIV+ donors into HIV+ recipients. Ongoing national studies are exploring the safety, feasibility, and efficacy of both kidney and liver transplantation in this population. If successfully and fully implemented, HIV+ to HIV+ transplantation could attenuate the organ shortage for everyone waiting, resulting in a far-reaching public health impact.

Original languageEnglish (US)
Pages (from-to)434-440
Number of pages7
JournalCurrent opinion in organ transplantation
Volume24
Issue number4
DOIs
StatePublished - Aug 1 2019

Keywords

  • end-stage renal disease
  • HIV infection
  • HIV Organ Policy Equity Act
  • kidney transplant
  • solid organ transplantation

ASJC Scopus subject areas

  • Immunology and Allergy
  • Transplantation

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