The functional properties of the G protein-coupled receptor melanopsin in intrinsically photosensitive retinal ganglion cells: Novel photoreceptors controlling diverse visual functions

Alan C. Rupp; Samer Hattar

doi:10.1007/978-1-4939-1218-6_10

The functional properties of the G protein-coupled receptor melanopsin in intrinsically photosensitive retinal ganglion cells: Novel photoreceptors controlling diverse visual functions

Alan C. Rupp, Samer Hattar

School of Arts and Sciences

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Only slightly over a decade ago, the rods and cones in the outer retina were thought to be the exclusive photoreceptors in mammals. Since then, the discovery of an additional photopigment melanopsin (a G protein-coupled receptor, GPCR) expressed in a small subset of intrinsically photosensitive retinal ganglion cells (ipRGCs) has expanded upon the conventional view of light detection and information flow in the retina. In this chapter, we will highlight our current understanding of the structure and function of melanopsin, the cell biology and physiology of ipRGCs, how ipRGCs are integrated into the retinal circuitry, and the role of ipRGCs in visual behaviors.

Original language	English (US)
Title of host publication	G Protein Signaling Mechanisms in the Retina
Publisher	Springer New York
Pages	173-195
Number of pages	23
ISBN (Electronic)	9781493912186
ISBN (Print)	9781493912179
DOIs	https://doi.org/10.1007/978-1-4939-1218-6_10
State	Published - Jan 1 2014

ASJC Scopus subject areas

Medicine(all)
Neuroscience(all)

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10.1007/978-1-4939-1218-6_10

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The functional properties of the G protein-coupled receptor melanopsin in intrinsically photosensitive retinal ganglion cells : Novel photoreceptors controlling diverse visual functions. / Rupp, Alan C.; Hattar, Samer.

G Protein Signaling Mechanisms in the Retina. Springer New York, 2014. p. 173-195.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

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The functional properties of the G protein-coupled receptor melanopsin in intrinsically photosensitive retinal ganglion cells: Novel photoreceptors controlling diverse visual functions

Abstract

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