The frontal lobes and schizophrenia

Daniel Weinberger, M. S. Aloia, T. E. Goldberg, K. F. Berman

Research output: Contribution to journalReview article

Abstract

Many patients with schizophrenia show clinical signs of frontal lobe dysfunction, including blunted affect, difficulty with problem solving, and impoverished thinking. The authors present cytoarchitectural, neuropsychological, and functional neuroanatomical evidence of frontal abnormalities from recent studies of frontal dysfunction in schizophrenia. It is suggested that the failure of intracortical connectivity of the prefrontal cortex accounts for both cognitive and psychotic manifestations of this illness.

Original languageEnglish (US)
Pages (from-to)419-427
Number of pages9
JournalJournal of Neuropsychiatry and Clinical Neurosciences
Volume6
Issue number4
StatePublished - 1994
Externally publishedYes

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Frontal Lobe
Schizophrenia
Neurobehavioral Manifestations
Prefrontal Cortex
Thinking

ASJC Scopus subject areas

  • Neuroscience(all)
  • Neuropsychology and Physiological Psychology

Cite this

Weinberger, D., Aloia, M. S., Goldberg, T. E., & Berman, K. F. (1994). The frontal lobes and schizophrenia. Journal of Neuropsychiatry and Clinical Neurosciences, 6(4), 419-427.

The frontal lobes and schizophrenia. / Weinberger, Daniel; Aloia, M. S.; Goldberg, T. E.; Berman, K. F.

In: Journal of Neuropsychiatry and Clinical Neurosciences, Vol. 6, No. 4, 1994, p. 419-427.

Research output: Contribution to journalReview article

Weinberger, D, Aloia, MS, Goldberg, TE & Berman, KF 1994, 'The frontal lobes and schizophrenia', Journal of Neuropsychiatry and Clinical Neurosciences, vol. 6, no. 4, pp. 419-427.
Weinberger, Daniel ; Aloia, M. S. ; Goldberg, T. E. ; Berman, K. F. / The frontal lobes and schizophrenia. In: Journal of Neuropsychiatry and Clinical Neurosciences. 1994 ; Vol. 6, No. 4. pp. 419-427.
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