The first chemical synthesis of boronic acid-modified DNA through a copper-free click reaction

Chaofeng Dai, Lifang Wang, Jia Sheng, Hanjing Peng, Alexander Boryanov Draganov, Zhen Huang, Binghe Wang

Research output: Contribution to journalArticlepeer-review

Abstract

The first chemical incorporation of the boronic acid group into DNA using a copper-free click reagent was reported. Compared with the PCR-based method, this approach allows for site-specific incorporation and synthesis on a larger scale.

Original languageEnglish (US)
Pages (from-to)3598-3600
Number of pages3
JournalChemical Communications
Volume47
Issue number12
DOIs
StatePublished - Mar 8 2011
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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