The Eye in Bone Marrow Transplantation: I. Clinical Study

Lawrence W. Hirst, Douglas Jabs, Peter J. Tutschka, George W. Santos, W. Richard Green

Research output: Contribution to journalArticle

Abstract

A prospective study of 45 patients undergoing bone marrow transplantation included full ocular examination and pretransplant and posttransplant conjunctival biopsies. The major finding was the development of a severe keratoconjunctivitis sicca syndrome that developed in 20 of the 45 patients and closely correlated with the occurrence of acute graft-v-host disease (GVHD). An acute pseudomembranous conjunctivitis in the fulminant stage of acute GVHD developed in six patients. A further ten patients made up a retrospective assessment of bone marrow transplantation and confirmed these clinical findings.

Original languageEnglish (US)
Pages (from-to)580-584
Number of pages5
JournalArchives of ophthalmology
Volume101
Issue number4
DOIs
StatePublished - Jan 1 1983

Fingerprint

Bone Marrow Transplantation
Keratoconjunctivitis Sicca
Transplants
Conjunctivitis
Sjogren's Syndrome
Prospective Studies
Biopsy
Clinical Studies

ASJC Scopus subject areas

  • Ophthalmology

Cite this

The Eye in Bone Marrow Transplantation : I. Clinical Study. / Hirst, Lawrence W.; Jabs, Douglas; Tutschka, Peter J.; Santos, George W.; Green, W. Richard.

In: Archives of ophthalmology, Vol. 101, No. 4, 01.01.1983, p. 580-584.

Research output: Contribution to journalArticle

Hirst, Lawrence W. ; Jabs, Douglas ; Tutschka, Peter J. ; Santos, George W. ; Green, W. Richard. / The Eye in Bone Marrow Transplantation : I. Clinical Study. In: Archives of ophthalmology. 1983 ; Vol. 101, No. 4. pp. 580-584.
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