Abstract
A prospective study of 45 patients undergoing bone marrow transplantation included full ocular examination and pretransplant and posttransplant conjunctival biopsies. The major finding was the development of a severe keratoconjunctivitis sicca syndrome that developed in 20 of the 45 patients and closely correlated with the occurrence of acute graft-v-host disease (GVHD). An acute pseudomembranous conjunctivitis in the fulminant stage of acute GVHD developed in six patients. A further ten patients made up a retrospective assessment of bone marrow transplantation and confirmed these clinical findings.
Original language | English (US) |
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Pages (from-to) | 580-584 |
Number of pages | 5 |
Journal | Archives of ophthalmology |
Volume | 101 |
Issue number | 4 |
DOIs | |
State | Published - Apr 1983 |
ASJC Scopus subject areas
- Ophthalmology