The evidence-based vulvodynia assessment project

A national registry for the study of vulvodynia

Georgine Lamvu, Ruby H N Nguyen, Lara J. Burrows, Andrea Rapkin, Kathryn Witzeman, Richard P. Marvel, David Hutchins, Steven S. Witkin, Christin Veasley, Roger Fillingim, Denniz Zolnoun

Research output: Contribution to journalArticle

Abstract

OBJECTIVE: To create a national registry for the study of vulvodynia in order to enhance classification of vulvodynia based on multiple phenotypic domains such as pain characteristics, clinical examination, sexual function, psychological functioning, and distress. STUDY DESIGN: Methodology for this prospective cohort registry was institutional review board approved and implemented at 8 enrollment sites starting in 2009. Women underwent gynecologic evaluation and pressure sensory testing for assessment of pain sensitivity in the vaginal mucosa and vaginal muscles. Psychometric questionnaires were used to assess self-described pain, distress, sexual function, and quality of life. RESULTS: More than 300 women were enrolled and 176 charts were analyzed. This cohort had a median age of 29 years and median pain duration of 25.5 months. A total of 84% of participants were previously or currently sexually active in spite of pain. The most common pain comorbidities reported by the women were migraines (34%), chronic pelvic pain (22%), and irritable bowel syndrome (20%). Anxiety affected 41% of the cohort. More than 90% presented with localized vestibular pain, and 90% had muscular examination abnormalities. CONCLUSION: A national registry for the study of vulvodynia was established with successful enrollment of participants at 8 sites. In addition to the cotton swab evaluation for vulvar allodynia, women with vulvar chronic pain should also be routinely screened for musculoskeletal dysfunction, emotional distress with specific emphasis on anxiety, and comorbid pain conditions.

Original languageEnglish (US)
Pages (from-to)223-235
Number of pages13
JournalJournal of Reproductive Medicine for the Obstetrician and Gynecologist
Volume60
Issue number3
StatePublished - Jun 1 2015

Fingerprint

Vulvodynia
Registries
Pain
Chronic Pain
Anxiety
Pelvic Pain
Irritable Bowel Syndrome
Research Ethics Committees
Hyperalgesia
Pain Measurement
Migraine Disorders
Psychometrics
Comorbidity
Mucous Membrane
Quality of Life
Psychology
Pressure
Muscles

Keywords

  • Chronic pain
  • Musculoskeletal pain
  • Registry
  • Vestibulitis
  • Vulva
  • Vulvar pain
  • Vulvodynia

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Reproductive Medicine

Cite this

Lamvu, G., Nguyen, R. H. N., Burrows, L. J., Rapkin, A., Witzeman, K., Marvel, R. P., ... Zolnoun, D. (2015). The evidence-based vulvodynia assessment project: A national registry for the study of vulvodynia. Journal of Reproductive Medicine for the Obstetrician and Gynecologist, 60(3), 223-235.

The evidence-based vulvodynia assessment project : A national registry for the study of vulvodynia. / Lamvu, Georgine; Nguyen, Ruby H N; Burrows, Lara J.; Rapkin, Andrea; Witzeman, Kathryn; Marvel, Richard P.; Hutchins, David; Witkin, Steven S.; Veasley, Christin; Fillingim, Roger; Zolnoun, Denniz.

In: Journal of Reproductive Medicine for the Obstetrician and Gynecologist, Vol. 60, No. 3, 01.06.2015, p. 223-235.

Research output: Contribution to journalArticle

Lamvu, G, Nguyen, RHN, Burrows, LJ, Rapkin, A, Witzeman, K, Marvel, RP, Hutchins, D, Witkin, SS, Veasley, C, Fillingim, R & Zolnoun, D 2015, 'The evidence-based vulvodynia assessment project: A national registry for the study of vulvodynia', Journal of Reproductive Medicine for the Obstetrician and Gynecologist, vol. 60, no. 3, pp. 223-235.
Lamvu, Georgine ; Nguyen, Ruby H N ; Burrows, Lara J. ; Rapkin, Andrea ; Witzeman, Kathryn ; Marvel, Richard P. ; Hutchins, David ; Witkin, Steven S. ; Veasley, Christin ; Fillingim, Roger ; Zolnoun, Denniz. / The evidence-based vulvodynia assessment project : A national registry for the study of vulvodynia. In: Journal of Reproductive Medicine for the Obstetrician and Gynecologist. 2015 ; Vol. 60, No. 3. pp. 223-235.
@article{0a5584fb64b34581bcd7a5884f754c57,
title = "The evidence-based vulvodynia assessment project: A national registry for the study of vulvodynia",
abstract = "OBJECTIVE: To create a national registry for the study of vulvodynia in order to enhance classification of vulvodynia based on multiple phenotypic domains such as pain characteristics, clinical examination, sexual function, psychological functioning, and distress. STUDY DESIGN: Methodology for this prospective cohort registry was institutional review board approved and implemented at 8 enrollment sites starting in 2009. Women underwent gynecologic evaluation and pressure sensory testing for assessment of pain sensitivity in the vaginal mucosa and vaginal muscles. Psychometric questionnaires were used to assess self-described pain, distress, sexual function, and quality of life. RESULTS: More than 300 women were enrolled and 176 charts were analyzed. This cohort had a median age of 29 years and median pain duration of 25.5 months. A total of 84{\%} of participants were previously or currently sexually active in spite of pain. The most common pain comorbidities reported by the women were migraines (34{\%}), chronic pelvic pain (22{\%}), and irritable bowel syndrome (20{\%}). Anxiety affected 41{\%} of the cohort. More than 90{\%} presented with localized vestibular pain, and 90{\%} had muscular examination abnormalities. CONCLUSION: A national registry for the study of vulvodynia was established with successful enrollment of participants at 8 sites. In addition to the cotton swab evaluation for vulvar allodynia, women with vulvar chronic pain should also be routinely screened for musculoskeletal dysfunction, emotional distress with specific emphasis on anxiety, and comorbid pain conditions.",
keywords = "Chronic pain, Musculoskeletal pain, Registry, Vestibulitis, Vulva, Vulvar pain, Vulvodynia",
author = "Georgine Lamvu and Nguyen, {Ruby H N} and Burrows, {Lara J.} and Andrea Rapkin and Kathryn Witzeman and Marvel, {Richard P.} and David Hutchins and Witkin, {Steven S.} and Christin Veasley and Roger Fillingim and Denniz Zolnoun",
year = "2015",
month = "6",
day = "1",
language = "English (US)",
volume = "60",
pages = "223--235",
journal = "The Journal of reproductive medicine",
issn = "0024-7758",
publisher = "Donna Kessel",
number = "3",

}

TY - JOUR

T1 - The evidence-based vulvodynia assessment project

T2 - A national registry for the study of vulvodynia

AU - Lamvu, Georgine

AU - Nguyen, Ruby H N

AU - Burrows, Lara J.

AU - Rapkin, Andrea

AU - Witzeman, Kathryn

AU - Marvel, Richard P.

AU - Hutchins, David

AU - Witkin, Steven S.

AU - Veasley, Christin

AU - Fillingim, Roger

AU - Zolnoun, Denniz

PY - 2015/6/1

Y1 - 2015/6/1

N2 - OBJECTIVE: To create a national registry for the study of vulvodynia in order to enhance classification of vulvodynia based on multiple phenotypic domains such as pain characteristics, clinical examination, sexual function, psychological functioning, and distress. STUDY DESIGN: Methodology for this prospective cohort registry was institutional review board approved and implemented at 8 enrollment sites starting in 2009. Women underwent gynecologic evaluation and pressure sensory testing for assessment of pain sensitivity in the vaginal mucosa and vaginal muscles. Psychometric questionnaires were used to assess self-described pain, distress, sexual function, and quality of life. RESULTS: More than 300 women were enrolled and 176 charts were analyzed. This cohort had a median age of 29 years and median pain duration of 25.5 months. A total of 84% of participants were previously or currently sexually active in spite of pain. The most common pain comorbidities reported by the women were migraines (34%), chronic pelvic pain (22%), and irritable bowel syndrome (20%). Anxiety affected 41% of the cohort. More than 90% presented with localized vestibular pain, and 90% had muscular examination abnormalities. CONCLUSION: A national registry for the study of vulvodynia was established with successful enrollment of participants at 8 sites. In addition to the cotton swab evaluation for vulvar allodynia, women with vulvar chronic pain should also be routinely screened for musculoskeletal dysfunction, emotional distress with specific emphasis on anxiety, and comorbid pain conditions.

AB - OBJECTIVE: To create a national registry for the study of vulvodynia in order to enhance classification of vulvodynia based on multiple phenotypic domains such as pain characteristics, clinical examination, sexual function, psychological functioning, and distress. STUDY DESIGN: Methodology for this prospective cohort registry was institutional review board approved and implemented at 8 enrollment sites starting in 2009. Women underwent gynecologic evaluation and pressure sensory testing for assessment of pain sensitivity in the vaginal mucosa and vaginal muscles. Psychometric questionnaires were used to assess self-described pain, distress, sexual function, and quality of life. RESULTS: More than 300 women were enrolled and 176 charts were analyzed. This cohort had a median age of 29 years and median pain duration of 25.5 months. A total of 84% of participants were previously or currently sexually active in spite of pain. The most common pain comorbidities reported by the women were migraines (34%), chronic pelvic pain (22%), and irritable bowel syndrome (20%). Anxiety affected 41% of the cohort. More than 90% presented with localized vestibular pain, and 90% had muscular examination abnormalities. CONCLUSION: A national registry for the study of vulvodynia was established with successful enrollment of participants at 8 sites. In addition to the cotton swab evaluation for vulvar allodynia, women with vulvar chronic pain should also be routinely screened for musculoskeletal dysfunction, emotional distress with specific emphasis on anxiety, and comorbid pain conditions.

KW - Chronic pain

KW - Musculoskeletal pain

KW - Registry

KW - Vestibulitis

KW - Vulva

KW - Vulvar pain

KW - Vulvodynia

UR - http://www.scopus.com/inward/record.url?scp=84957868467&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84957868467&partnerID=8YFLogxK

M3 - Article

VL - 60

SP - 223

EP - 235

JO - The Journal of reproductive medicine

JF - The Journal of reproductive medicine

SN - 0024-7758

IS - 3

ER -