Abstract
This perspective on the report by Benchekroun et al. in this issue of the journal (beginning on page 800) examines new studies of factors in the epidermal growth factor receptor (EGFR) axis (including copy number alterations at the EGFR locus) that potentially predict the development of oral cancer; this work was conducted in a chemoprevention trial cohort of patients with oral premalignant lesions. The new data raise the possibility that a subset of oral premalignant lesions may benefit from specific therapeutic targeting of the EGFR axis.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 797-799 |
| Number of pages | 3 |
| Journal | Cancer Prevention Research |
| Volume | 3 |
| Issue number | 7 |
| DOIs | |
| State | Published - Jul 2010 |
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ASJC Scopus subject areas
- Cancer Research
- Oncology
Cite this
The epidermal growth factor receptor axis : Support for a new target for oral premalignancy. / Rosin, Miriam P.; Califano, Joseph A.
In: Cancer Prevention Research, Vol. 3, No. 7, 07.2010, p. 797-799.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The epidermal growth factor receptor axis
T2 - Support for a new target for oral premalignancy
AU - Rosin, Miriam P.
AU - Califano, Joseph A.
PY - 2010/7
Y1 - 2010/7
N2 - This perspective on the report by Benchekroun et al. in this issue of the journal (beginning on page 800) examines new studies of factors in the epidermal growth factor receptor (EGFR) axis (including copy number alterations at the EGFR locus) that potentially predict the development of oral cancer; this work was conducted in a chemoprevention trial cohort of patients with oral premalignant lesions. The new data raise the possibility that a subset of oral premalignant lesions may benefit from specific therapeutic targeting of the EGFR axis.
AB - This perspective on the report by Benchekroun et al. in this issue of the journal (beginning on page 800) examines new studies of factors in the epidermal growth factor receptor (EGFR) axis (including copy number alterations at the EGFR locus) that potentially predict the development of oral cancer; this work was conducted in a chemoprevention trial cohort of patients with oral premalignant lesions. The new data raise the possibility that a subset of oral premalignant lesions may benefit from specific therapeutic targeting of the EGFR axis.
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UR - http://www.scopus.com/inward/citedby.url?scp=77954725485&partnerID=8YFLogxK
U2 - 10.1158/1940-6207.CAPR-10-0114
DO - 10.1158/1940-6207.CAPR-10-0114
M3 - Article
C2 - 20570884
AN - SCOPUS:77954725485
VL - 3
SP - 797
EP - 799
JO - Cancer Prevention Research
JF - Cancer Prevention Research
SN - 1940-6207
IS - 7
ER -