The endovascular occlusion system for safe and immediate peripheral vessel occlusion during vascular interventions

Maximilian Y. Emmert, Anthony Venbrux, Leon Rudakov, Nikola Cesarovic, Martin G. Radvany, Philippe Gailloud, Volkmar Falk, Andre Plass

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Endovascular occlusion of blood vessels is an important part of interventional therapy concepts. Here, we evaluate the feasibility, procedural safety and efficacy of the novel endovascular occlusion system (EOS) in the arterial system in a porcine model. Thirteen devices were deployed in the iliac and femoral arteries (diameter: 4-5 mm) of five adult swine. Post-deployment angiography was performed at 1, 5 and 10 min and 6 h. All devices (n = 13) could be successfully delivered without any complications, such as dissection, perforation or rupture. The devices could be easily advanced to the target vessel segment, deployed at the intended target location and produced immediate and complete vessel occlusion which was confirmed to be maintained after 6 h. No leaks, recanalization or device migration was observed. In this pilot study, we demonstrate the feasibility, safety and efficacy of immediate vessel occlusion with the EOS device in the peripheral arterial system in a porcine animal model. Our data indicate that this novel device allows precise delivery without the occurrence of cardiovascular complications. Owing to its long-term safety and efficacy the EOS may represent a promising and effective alternative to currently available devices for vessel occlusion during vascular interventions.

Original languageEnglish (US)
Pages (from-to)882-885
Number of pages4
JournalInteractive cardiovascular and thoracic surgery
Volume17
Issue number5
DOIs
StatePublished - Nov 2013

Keywords

  • Embolization
  • Endovascular
  • Occlusion device
  • Vessel occlusion

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

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