Duodenoscopic examination of a patient with Whipple's disease revealed that the duodenal mucosa appeared to be partially covered with a yellow white material. On closer inspection, however, this was found to consist of enlarged villi interspersed with normal looking mucosa. Histologically these enlarged white villi were shown to contain a heavy accumulation of lipid and typical PAS positive macrophages. The duodenal mucosa was endoscopically normal and histologically showed only a few PAS positive macrophages one year after instituting antibiotic therapy.
|Original language||English (US)|
|Number of pages||5|
|Journal||Johns Hopkins Medical Journal|
|State||Published - Dec 1 1976|
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