The emerging links between sirtuins and autophagy

In Hye Lee, Jeanho Yun, Toren Finkel

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Evidence suggests a role for acetylation and deacetylation in regulating autophagy. In this chapter, we describe the methods useful for understanding this important connection. In particular, we discuss methods for the measurements of sirtuin deacetylase activity, in vivo acetylation detection, and the common assays used to monitor both autophagy and the more selective process of mitophagy.

Original languageEnglish (US)
Title of host publicationMethods in Molecular Biology
Pages259-271
Number of pages13
Volume1077
DOIs
StatePublished - 2013
Externally publishedYes

Publication series

NameMethods in Molecular Biology
Volume1077
ISSN (Print)10643745

Keywords

  • Atg
  • Autophagosome
  • Autophagy
  • Keima
  • LC3
  • p62

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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