Purpose: To determine the efficacy of grid laser therapy for radiation induced maculopathy. Methods: Retrospective chart review of patients with radiation retinopathy following episcleral plaque radiotherapy for choroidal melanoma identified twenty-seven cases with maculopathy managed by grid laser therapy and twenty-five followed without therapy. After exclusion of cases with co-existent cataract, neovascular glaucoma, vitreous haemorrhage and radiation papillopathy, the visual outcome was compared in seventeen treated and eighteen untreated cases. Results: At six months follow-up, visual acuity was unchanged in 13/17 (77%) of treated cases compared to 12/18 (67%) of untreated cases. At twelve months follow up, visual acuity was improved (≥2Snellen lines) in 2/14 treated cases, both with diffuse leakage and minimal macula ischemia and in 0/16 untreated cases. Visual acuity remained stable in 8/14 (57 %) of treated cases and in 5/16 (31%) of untreated cases, (Fischers Exact Test, p<0.26). Conclusions: Grid laser treatment for radiation maculopathy may be effective in occasional cases with diffuse edema and minimal ischemia but there appears to be no significant overall benefit from therapy.
|Original language||English (US)|
|Journal||Investigative Ophthalmology and Visual Science|
|State||Published - Feb 15 1996|
ASJC Scopus subject areas
- Sensory Systems
- Cellular and Molecular Neuroscience