The effects of varying sodium concentrations on the metabolism of glutamine by the renal cortex of the rat

Janet Hawthorn, Jennifer A. Alexander, George A O Alleyne

Research output: Contribution to journalArticle

Abstract

We studied the effect of varying the sodium concentration on the tissue swelling and metabolism of renal cortical slices from control and acidotic rats. Lowering the sodium concentration in the incubation medium caused increased tissue swelling and depressed glutamine uptake, ammoniagenesis and gluconeogenesis in slices from both control and acidotic rats.

Original languageEnglish (US)
Pages (from-to)140-146
Number of pages7
JournalKidney and Blood Pressure Research
Volume1
Issue number3
DOIs
StatePublished - 1978
Externally publishedYes

Keywords

  • Acidosis
  • Ammonia
  • Glucose
  • Glutamine
  • Sodium

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Nephrology

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