The effects of under 6 hours of formalin fixation on hormone receptor and HER2 expression in invasive breast cancer: A systematic review

Shona Kalkman; Maarten W. Barentsz; Paul J. Van Diest

doi:10.1309/AJCP96YDQSTYBXWU

The effects of under 6 hours of formalin fixation on hormone receptor and HER2 expression in invasive breast cancer: A systematic review

Shona Kalkman, Maarten W. Barentsz, Paul J. Van Diest

Research output: Contribution to journal › Article › peer-review

Abstract

Objectives: A systematic review of the literature was performed to identify whether minimum formalin fixation time may be reduced for reliable immunohistochemical assessment of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2). Methods: PubMed, EMBASE, and the Cochrane Library were systematically searched for studies addressing effects of brief tissue fixation (

Original language	English (US)
Pages (from-to)	16-22
Number of pages	7
Journal	American Journal of Clinical Pathology
Volume	142
Issue number	1
DOIs	https://doi.org/10.1309/AJCP96YDQSTYBXWU
State	Published - 2014
Externally published	Yes

Keywords

Breast cancel
Estrogen receptor
Fixation time
HER2
Immunohistochemistry
Progesterone receptor

ASJC Scopus subject areas

Pathology and Forensic Medicine

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10.1309/AJCP96YDQSTYBXWU

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KW - Fixation time

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KW - Immunohistochemistry

KW - Progesterone receptor

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The effects of under 6 hours of formalin fixation on hormone receptor and HER2 expression in invasive breast cancer: A systematic review

Abstract

Keywords

ASJC Scopus subject areas

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