The effects of electroconvulsive shock on catecholamine function in the locus ceruleus and hippocampus

N. Weiner, M. A. Hossain, J. M. Masserano

Research output: Contribution to journalArticle


Repeated electroconvulsive shock (ECS) treatment (once per day for 7 days) produced a significant increase in tyrosine hydroxylase activity, GTP-cyclohydrolase activity and tetrahydrobiopterin (BH4) levels in the locus ceruleus and hippocampus from 1 to 4 days after the last treatment. These changes may be responsible for, or contribute to, the antidepressant effect of ECS treatment.

Original languageEnglish (US)
Pages (from-to)3-9
Number of pages7
JournalJournal of Neural Transmission, Supplement
Issue number34
StatePublished - Dec 1 1991


ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology
  • Psychiatry and Mental health
  • Biological Psychiatry

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