The effects of DonorNet 2007 on kidney distribution equity and efficiency

Research output: Contribution to journalArticlepeer-review

Abstract

In 2007, UNOS released DonorNet 2007 ® (DN07) in hope of improving allocation equity and efficiency. We hypothesized that hard-to-place organs might be less efficiently handled through this regimented process. We analyzed associations between DN07 and center-level equity, number of refusals per organ and cold ischemia time (CIT). A total of 8244 kidney transplants between 1/2006 and 12/2006 (pre-DN07) were compared with 6029 transplants between 5/2007 and 2/2008 (post-DN07). Distribution equity was assessed by the Gini coefficient, changes in the number of refusals and CIT by negative binomial regression and discard rates by logistic regression. We estimated quantile-specific differences in CIT by bootstrapping. We found no significant change in center-level distribution equity after DN07. Number of refusals per organ increased by 20% (adjusted rate ratio 1.121.20 1.28, p < 0.001) at the patient level and 11% (ARR 1.071.11 1.16, p < 0.001) at the center level. Regression models of CIT showed no global change in CIT associated with DN07, but those kidneys with the longest CIT pre-DN07 had statistically significantly longer CIT post-DN07. The discard rate also increased significantly (ARR 1.061.11 1.17, p < 0.001). DN07 has not improved equity or efficiency in allocation of deceased donor kidneys, and may be harming the allocation of hard-to-place kidneys.

Original languageEnglish (US)
Pages (from-to)1550-1557
Number of pages8
JournalAmerican Journal of Transplantation
Volume9
Issue number7
DOIs
StatePublished - Jul 2009

Keywords

  • Cold ischemia time
  • Deceased donor transplantation
  • DonorNet 2007
  • Equity

ASJC Scopus subject areas

  • Immunology and Allergy
  • Transplantation
  • Pharmacology (medical)

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