TY - JOUR
T1 - The effects of brief exposures to carbon monoxide on temporally differentiated responding
AU - Ator, Nancy A.
AU - Merigan, William H.
AU - McIntire, Roger W.
N1 - Funding Information:
This research was supported in part by Public Health Service Grant No. ESOO757-02 from the National Institutes of Environmental Health. An earlier version of this paper was presented at the meetings of the American Psychological Association, New Orleans, 1974. The authors wish to thank Ms. Marcia Smith and Ms. Helen Reznick for their help in conducting this experiment. Appreciation is extended to Dr. Edward P. Radford ofJohns Hopkins School of Hygiene and Public Health for making the COHb determinations and to Dr. James E. Barrett and Jonathan L. Katz for their helpful comments on the manuscript.
Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.
PY - 1976/8
Y1 - 1976/8
N2 - Four rats were trained on a differential-reinforcement-of-low-rate schedule under which only responses separated by intervals of 21 seconds produced food. Ninety-minute exposures to 100, 250, 500, 600, 750, and 1000 ppm carbon monoxide were given. Overall response rates were lower than rates in control sessions for all subjects at 750 ppm and higher concentrations. Measures of temporal discrimination (distributions of interresponse times), however, were not disrupted. The primary effect of the higher concentrations of carbon monoxide was to produce extended pausing or complete cessation of responding at some point in the session. Until pausing occurred, however, the control rate and patterning of responding obtained. The results are consistent with the growing body of evidence that carbon monoxide has a general rate-decreasing effect but no specific effect on measures of temporal discrimination.
AB - Four rats were trained on a differential-reinforcement-of-low-rate schedule under which only responses separated by intervals of 21 seconds produced food. Ninety-minute exposures to 100, 250, 500, 600, 750, and 1000 ppm carbon monoxide were given. Overall response rates were lower than rates in control sessions for all subjects at 750 ppm and higher concentrations. Measures of temporal discrimination (distributions of interresponse times), however, were not disrupted. The primary effect of the higher concentrations of carbon monoxide was to produce extended pausing or complete cessation of responding at some point in the session. Until pausing occurred, however, the control rate and patterning of responding obtained. The results are consistent with the growing body of evidence that carbon monoxide has a general rate-decreasing effect but no specific effect on measures of temporal discrimination.
UR - http://www.scopus.com/inward/record.url?scp=0017083851&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0017083851&partnerID=8YFLogxK
U2 - 10.1016/0013-9351(76)90011-6
DO - 10.1016/0013-9351(76)90011-6
M3 - Article
AN - SCOPUS:0017083851
VL - 12
SP - 81
EP - 91
JO - Environmental Research
JF - Environmental Research
SN - 0013-9351
IS - 1
ER -