The effect of vaginal douching cessation on bacterial vaginosis

a pilot study

Research output: Contribution to journalArticle

Abstract

Objective: The objective of the study was to evaluate the risk for bacterial vaginosis (BV) in a douching cessation trial. Study Design: Thirty-nine reproductive-age women who reported use of douche products were enrolled into a 20-week study consisting of a 4 week douching observation (phase I) followed by 12-weeks of douching cessation (phase II). In phase III, participants then chose to resume douching or continue cessation for the remaining 4 weeks. Self-collected vaginal samples were obtained twice weekly in the first 16 weeks, and 1 sample was collected during week 20 (1107 samples total). BV was diagnosed by Nugent score of 7 or greater. Conditional logistic regression was used to evaluate douching cessation on the risk of BV. Results: The adjusted odds ratio (aOR) for BV in the douching cessation phase, as compared with the douching-observation phase was 0.76 (95% confidence interval [CI], 0.33 to 1.76). Among women who reported their primary reason for douching was to cleanse after menstruation, BV was significantly reduced in douching cessation (aOR:0.23; 95% CI, 0.12 to 0.44). Conclusion: Vaginal douching cessation may reduce the risk for BV in a subset of women.

Original languageEnglish (US)
JournalAmerican Journal of Obstetrics and Gynecology
Volume198
Issue number6
DOIs
StatePublished - Jun 2008

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Vaginal Douching
Bacterial Vaginosis
Therapeutic Irrigation
Odds Ratio
Observation
Confidence Intervals
Menstruation
Logistic Models

Keywords

  • bacterial vaginosis
  • intravaginal cleansing
  • intravaginal washing
  • vaginal douching

ASJC Scopus subject areas

  • Medicine(all)
  • Obstetrics and Gynecology

Cite this

@article{c91e78db9a544d10a319a4677ea3f10f,
title = "The effect of vaginal douching cessation on bacterial vaginosis: a pilot study",
abstract = "Objective: The objective of the study was to evaluate the risk for bacterial vaginosis (BV) in a douching cessation trial. Study Design: Thirty-nine reproductive-age women who reported use of douche products were enrolled into a 20-week study consisting of a 4 week douching observation (phase I) followed by 12-weeks of douching cessation (phase II). In phase III, participants then chose to resume douching or continue cessation for the remaining 4 weeks. Self-collected vaginal samples were obtained twice weekly in the first 16 weeks, and 1 sample was collected during week 20 (1107 samples total). BV was diagnosed by Nugent score of 7 or greater. Conditional logistic regression was used to evaluate douching cessation on the risk of BV. Results: The adjusted odds ratio (aOR) for BV in the douching cessation phase, as compared with the douching-observation phase was 0.76 (95{\%} confidence interval [CI], 0.33 to 1.76). Among women who reported their primary reason for douching was to cleanse after menstruation, BV was significantly reduced in douching cessation (aOR:0.23; 95{\%} CI, 0.12 to 0.44). Conclusion: Vaginal douching cessation may reduce the risk for BV in a subset of women.",
keywords = "bacterial vaginosis, intravaginal cleansing, intravaginal washing, vaginal douching",
author = "Brotman, {Rebecca M.} and Ghanem, {Khalil G} and Klebanoff, {Mark A.} and Taha, {Taha E} and Scharfstein, {Daniel O} and Zenilman, {Jonathan Mark}",
year = "2008",
month = "6",
doi = "10.1016/j.ajog.2007.11.043",
language = "English (US)",
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journal = "American Journal of Obstetrics and Gynecology",
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T1 - The effect of vaginal douching cessation on bacterial vaginosis

T2 - a pilot study

AU - Brotman, Rebecca M.

AU - Ghanem, Khalil G

AU - Klebanoff, Mark A.

AU - Taha, Taha E

AU - Scharfstein, Daniel O

AU - Zenilman, Jonathan Mark

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N2 - Objective: The objective of the study was to evaluate the risk for bacterial vaginosis (BV) in a douching cessation trial. Study Design: Thirty-nine reproductive-age women who reported use of douche products were enrolled into a 20-week study consisting of a 4 week douching observation (phase I) followed by 12-weeks of douching cessation (phase II). In phase III, participants then chose to resume douching or continue cessation for the remaining 4 weeks. Self-collected vaginal samples were obtained twice weekly in the first 16 weeks, and 1 sample was collected during week 20 (1107 samples total). BV was diagnosed by Nugent score of 7 or greater. Conditional logistic regression was used to evaluate douching cessation on the risk of BV. Results: The adjusted odds ratio (aOR) for BV in the douching cessation phase, as compared with the douching-observation phase was 0.76 (95% confidence interval [CI], 0.33 to 1.76). Among women who reported their primary reason for douching was to cleanse after menstruation, BV was significantly reduced in douching cessation (aOR:0.23; 95% CI, 0.12 to 0.44). Conclusion: Vaginal douching cessation may reduce the risk for BV in a subset of women.

AB - Objective: The objective of the study was to evaluate the risk for bacterial vaginosis (BV) in a douching cessation trial. Study Design: Thirty-nine reproductive-age women who reported use of douche products were enrolled into a 20-week study consisting of a 4 week douching observation (phase I) followed by 12-weeks of douching cessation (phase II). In phase III, participants then chose to resume douching or continue cessation for the remaining 4 weeks. Self-collected vaginal samples were obtained twice weekly in the first 16 weeks, and 1 sample was collected during week 20 (1107 samples total). BV was diagnosed by Nugent score of 7 or greater. Conditional logistic regression was used to evaluate douching cessation on the risk of BV. Results: The adjusted odds ratio (aOR) for BV in the douching cessation phase, as compared with the douching-observation phase was 0.76 (95% confidence interval [CI], 0.33 to 1.76). Among women who reported their primary reason for douching was to cleanse after menstruation, BV was significantly reduced in douching cessation (aOR:0.23; 95% CI, 0.12 to 0.44). Conclusion: Vaginal douching cessation may reduce the risk for BV in a subset of women.

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