The effect of treatment with nitrendipine and other calcium channel blockers on the physiologic and pathologic changes caused by hypoxia in rats

John R. Michael, Thomas P. Kennedy, Philip Buescher, Imad Farrukh, Peter C. Rock, Gail Gurtner, Suzanne M. de la Monte, Grover M. Hutchins

Research output: Contribution to journalArticlepeer-review

Abstract

Nitrendipine and other calcium channel blokers acutely inhibit hypoxic pulmonary vasoconstriction and show promise in the prevention of the pulmonary vascular and cardiac changes produced by chronic alveolar hypoxia. This paper reviews the current information available from animal and clinical studies.

Original languageEnglish (US)
Pages (from-to)S61-S65
JournalJournal of cardiovascular pharmacology
Volume9
DOIs
StatePublished - Jan 1 1987

Keywords

  • Alveolar hypoxia
  • Nitrendipine
  • Pulmonary and cardiac changes

ASJC Scopus subject areas

  • Pharmacology
  • Cardiology and Cardiovascular Medicine

Fingerprint Dive into the research topics of 'The effect of treatment with nitrendipine and other calcium channel blockers on the physiologic and pathologic changes caused by hypoxia in rats'. Together they form a unique fingerprint.

Cite this