The Effect of Radiation Dose on Swallowing: Evaluation of Aspiration and Kinematics

Heather M. Starmer, Harry Quon, Rachit Kumar, Sara Alcorn, Emi Murano, Bronwyn Jones, Ianessa Humbert

Research output: Contribution to journalArticle

Abstract

Radiation oncologists have focused on the pharyngeal constrictors as the primary muscles of concern for dysphagia. However, our prior investigations have demonstrated that radiation dose to the geniohyoid rather than the constrictor muscles was more closely related to penetration aspiration scores (PAS). We examined the relationship between (1) radiation dose and swallowing temporal kinematics, and (2) between PAS and swallowing kinematics in these patients. Videofluoroscopic swallowing studies of 41 patients following radiation therapy for oropharyngeal cancer were analyzed for thin liquid boluses. Timing measures included duration of laryngeal vestibule closure (DLVC), duration to maximum hyoid elevation (DTMHE), duration to cricopharyngeal opening (DTCPO), and pharyngeal transit time (PTT). PAS was extracted for each swallow and considered normal if ≤2. As minimum and mean dose to the geniohyoid increased, DTMHE, DTCPO, and PTT increased. Worse PA scores were most strongly correlated with radiation dose received by geniohyoid (r = 0.445, p 

Original languageEnglish (US)
Pages (from-to)430-437
Number of pages8
JournalDysphagia
Volume30
Issue number4
DOIs
StatePublished - May 30 2015

Fingerprint

Radiation Effects
Deglutition
Biomechanical Phenomena
Radiation
Oropharyngeal Neoplasms
Muscles
Deglutition Disorders
Radiotherapy

Keywords

  • Deglutition
  • Deglutition disorders
  • Dysphagia
  • Head and neck cancer
  • Radiation oncology
  • Swallowing kinematics

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Gastroenterology
  • Speech and Hearing

Cite this

The Effect of Radiation Dose on Swallowing : Evaluation of Aspiration and Kinematics. / Starmer, Heather M.; Quon, Harry; Kumar, Rachit; Alcorn, Sara; Murano, Emi; Jones, Bronwyn; Humbert, Ianessa.

In: Dysphagia, Vol. 30, No. 4, 30.05.2015, p. 430-437.

Research output: Contribution to journalArticle

Starmer, Heather M. ; Quon, Harry ; Kumar, Rachit ; Alcorn, Sara ; Murano, Emi ; Jones, Bronwyn ; Humbert, Ianessa. / The Effect of Radiation Dose on Swallowing : Evaluation of Aspiration and Kinematics. In: Dysphagia. 2015 ; Vol. 30, No. 4. pp. 430-437.
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