Abstract
ABSTRACT— The X‐ray contrast material metrizamide is structurally related to 2‐deoxyglucose and inhibits brain glucose phosphorylation in vitro. In vivo, the present autoradiographic study with labeled 2‐deoxyglucose revealed a global reduction of brain glucose phosphorylation after metrizamide administration in the cisterna magna of rats. The reduction averaged 18% of all regions.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 249-253 |
| Number of pages | 5 |
| Journal | Acta Neurologica Scandinavica |
| Volume | 69 |
| Issue number | 4 |
| DOIs | |
| State | Published - Apr 1984 |
| Externally published | Yes |
Keywords
- Brain glucose consumption
- deoxyglucose
- metrizamide
- quantitative autoradiography
ASJC Scopus subject areas
- Neurology
- Clinical Neurology