The effect of location and configuration on forearm and upper arm hemodialysis arteriovenous grafts Presented at the 2013 Vascular Annual Meeting for the Society of Vascular Surgery, San Francisco, Calif, May 30-June 1, 2013.

Dialysis Access Consortium (DAC) Study Group

Research output: Contribution to journalArticle

Abstract

Objective The arteriovenous graft (AVG) is most often used in hemodialysis patients when an autogenous fistula is not feasible. The optimal location (forearm or upper arm) and configuration (loop or straight) of AVGs are not known. To evaluate relationships of AVG location and configuration with patency, we conducted a secondary analysis using data from a randomized, placebo-controlled trial of dipyridamole plus aspirin for newly placed AVG. Methods Participants of the Dialysis Access Consortium (DAC) Graft Study with newly placed upper extremity prosthetic grafts involving the brachial artery were studied. Multivariable analyses adjusting for trial treatment group, center, gender, race, body mass index, diabetes, current treatment with chronic dialysis, and prior arteriovenous vascular access or central venous catheter were performed to compare outcomes of forearm (fAVG) and upper arm (uAVG) grafts, including loss of primary unassisted patency (LPUP) and cumulative primary graft failure (CGF). Subgroup analyses of graft configuration and outflow vein used were also conducted. Results A total of 508 of the 649 participants (78%) enrolled in the trial had an upper extremity brachial artery graft placed, 255 with fAVG and 253 with uAVG. Participants with fAVG were less often male (33% vs 43%; P =.03), African American (62% vs 78%; P

Original languageEnglish (US)
Pages (from-to)1258-1265
Number of pages8
JournalJournal of Vascular Surgery
Volume62
Issue number5
DOIs
StatePublished - Nov 1 2015

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San Francisco
Forearm
Blood Vessels
Renal Dialysis
Arm
Transplants
Brachial Artery
Upper Extremity
Dialysis
Dipyridamole
Central Venous Catheters
African Americans
Aspirin
Fistula
Veins
Body Mass Index
Randomized Controlled Trials
Placebos

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

Cite this

@article{cb9507f234134bdf9ed2857c049eb9f4,
title = "The effect of location and configuration on forearm and upper arm hemodialysis arteriovenous grafts Presented at the 2013 Vascular Annual Meeting for the Society of Vascular Surgery, San Francisco, Calif, May 30-June 1, 2013.",
abstract = "Objective The arteriovenous graft (AVG) is most often used in hemodialysis patients when an autogenous fistula is not feasible. The optimal location (forearm or upper arm) and configuration (loop or straight) of AVGs are not known. To evaluate relationships of AVG location and configuration with patency, we conducted a secondary analysis using data from a randomized, placebo-controlled trial of dipyridamole plus aspirin for newly placed AVG. Methods Participants of the Dialysis Access Consortium (DAC) Graft Study with newly placed upper extremity prosthetic grafts involving the brachial artery were studied. Multivariable analyses adjusting for trial treatment group, center, gender, race, body mass index, diabetes, current treatment with chronic dialysis, and prior arteriovenous vascular access or central venous catheter were performed to compare outcomes of forearm (fAVG) and upper arm (uAVG) grafts, including loss of primary unassisted patency (LPUP) and cumulative primary graft failure (CGF). Subgroup analyses of graft configuration and outflow vein used were also conducted. Results A total of 508 of the 649 participants (78{\%}) enrolled in the trial had an upper extremity brachial artery graft placed, 255 with fAVG and 253 with uAVG. Participants with fAVG were less often male (33{\%} vs 43{\%}; P =.03), African American (62{\%} vs 78{\%}; P",
author = "{Dialysis Access Consortium (DAC) Study Group} and Alik Farber and Tan, {Tze Woei} and Bo Hu and Dember, {Laura M.} and Beck, {Gerald J.} and Dixon, {Bradley S.} and Kusek, {John W.} and Feldman, {Harold I.} and L. Dember and J. Kaufman and M. Hawley and A. Lauer and P. Lesage and R. Nathan and E. Holmberg and G. Braden and M. Ryan and A. Berkowitz and A. Rahman and B. Lucas and R. Santos and B. Reyes and A. Greenberg and M. Berkoben and E. Kovalik and J. Lawson and J. Middleton and S. Schwab and D. Schumm and S. Adams and K. Gitter and T. Cantaffa and A. Quarles and J. Work and S. Rhodes and J. Himmelfarb and J. Whiting and J. Kane and S. Freedman and R. Violette and H. Cyr-Alves and K. Garrison and K. Martin and P. Schmitz and V. Jenkins and J. Cotton and E. Husband and M. Allon and M. Robbin and Marie Diener-West",
year = "2015",
month = "11",
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doi = "10.1016/j.jvs.2015.06.132",
language = "English (US)",
volume = "62",
pages = "1258--1265",
journal = "Journal of Vascular Surgery",
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TY - JOUR

T1 - The effect of location and configuration on forearm and upper arm hemodialysis arteriovenous grafts Presented at the 2013 Vascular Annual Meeting for the Society of Vascular Surgery, San Francisco, Calif, May 30-June 1, 2013.

AU - Dialysis Access Consortium (DAC) Study Group

AU - Farber, Alik

AU - Tan, Tze Woei

AU - Hu, Bo

AU - Dember, Laura M.

AU - Beck, Gerald J.

AU - Dixon, Bradley S.

AU - Kusek, John W.

AU - Feldman, Harold I.

AU - Dember, L.

AU - Kaufman, J.

AU - Hawley, M.

AU - Lauer, A.

AU - Lesage, P.

AU - Nathan, R.

AU - Holmberg, E.

AU - Braden, G.

AU - Ryan, M.

AU - Berkowitz, A.

AU - Rahman, A.

AU - Lucas, B.

AU - Santos, R.

AU - Reyes, B.

AU - Greenberg, A.

AU - Berkoben, M.

AU - Kovalik, E.

AU - Lawson, J.

AU - Middleton, J.

AU - Schwab, S.

AU - Schumm, D.

AU - Adams, S.

AU - Gitter, K.

AU - Cantaffa, T.

AU - Quarles, A.

AU - Work, J.

AU - Rhodes, S.

AU - Himmelfarb, J.

AU - Whiting, J.

AU - Kane, J.

AU - Freedman, S.

AU - Violette, R.

AU - Cyr-Alves, H.

AU - Garrison, K.

AU - Martin, K.

AU - Schmitz, P.

AU - Jenkins, V.

AU - Cotton, J.

AU - Husband, E.

AU - Allon, M.

AU - Robbin, M.

AU - Diener-West, Marie

PY - 2015/11/1

Y1 - 2015/11/1

N2 - Objective The arteriovenous graft (AVG) is most often used in hemodialysis patients when an autogenous fistula is not feasible. The optimal location (forearm or upper arm) and configuration (loop or straight) of AVGs are not known. To evaluate relationships of AVG location and configuration with patency, we conducted a secondary analysis using data from a randomized, placebo-controlled trial of dipyridamole plus aspirin for newly placed AVG. Methods Participants of the Dialysis Access Consortium (DAC) Graft Study with newly placed upper extremity prosthetic grafts involving the brachial artery were studied. Multivariable analyses adjusting for trial treatment group, center, gender, race, body mass index, diabetes, current treatment with chronic dialysis, and prior arteriovenous vascular access or central venous catheter were performed to compare outcomes of forearm (fAVG) and upper arm (uAVG) grafts, including loss of primary unassisted patency (LPUP) and cumulative primary graft failure (CGF). Subgroup analyses of graft configuration and outflow vein used were also conducted. Results A total of 508 of the 649 participants (78%) enrolled in the trial had an upper extremity brachial artery graft placed, 255 with fAVG and 253 with uAVG. Participants with fAVG were less often male (33% vs 43%; P =.03), African American (62% vs 78%; P

AB - Objective The arteriovenous graft (AVG) is most often used in hemodialysis patients when an autogenous fistula is not feasible. The optimal location (forearm or upper arm) and configuration (loop or straight) of AVGs are not known. To evaluate relationships of AVG location and configuration with patency, we conducted a secondary analysis using data from a randomized, placebo-controlled trial of dipyridamole plus aspirin for newly placed AVG. Methods Participants of the Dialysis Access Consortium (DAC) Graft Study with newly placed upper extremity prosthetic grafts involving the brachial artery were studied. Multivariable analyses adjusting for trial treatment group, center, gender, race, body mass index, diabetes, current treatment with chronic dialysis, and prior arteriovenous vascular access or central venous catheter were performed to compare outcomes of forearm (fAVG) and upper arm (uAVG) grafts, including loss of primary unassisted patency (LPUP) and cumulative primary graft failure (CGF). Subgroup analyses of graft configuration and outflow vein used were also conducted. Results A total of 508 of the 649 participants (78%) enrolled in the trial had an upper extremity brachial artery graft placed, 255 with fAVG and 253 with uAVG. Participants with fAVG were less often male (33% vs 43%; P =.03), African American (62% vs 78%; P

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U2 - 10.1016/j.jvs.2015.06.132

DO - 10.1016/j.jvs.2015.06.132

M3 - Article

C2 - 26254823

AN - SCOPUS:84945491960

VL - 62

SP - 1258

EP - 1265

JO - Journal of Vascular Surgery

JF - Journal of Vascular Surgery

SN - 0741-5214

IS - 5

ER -