The effect of indomethacin tocolysis on maternal coagulation status

Chad C. Lunt, Andrew Satin, William H. Barth, Gary D V Hankins

Research output: Contribution to journalArticle

Abstract

Objective: To investigate the effect of indomethacin tocolysis on maternal coagulation. Methods: Twenty gravidas at 24-32 weeks’ gestation were treated for preterm labor with 50 mg indomethacin orally, followed by 25 mg every 6 hours for 3 days. Bleeding time, prothrombin time (PT), and activated partial thromboplastin time (aPTT) were measured before and 48 hours after initiation of therapy. Statistical analysis was performed by paired t test and Fisher exact test. Results: The typical participant was 22 years old, nulliparous, and 26.2 weeks’ gestational age at enrollment. The mean bleeding time was 4.5 minutes before therapy and 8.8 minutes after therapy (P

Original languageEnglish (US)
Pages (from-to)820-822
Number of pages3
JournalObstetrics and Gynecology
Volume84
Issue number5
StatePublished - 1994
Externally publishedYes

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Tocolysis
Indomethacin
Bleeding Time
Mothers
Partial Thromboplastin Time
Premature Obstetric Labor
Prothrombin Time
Gestational Age
Therapeutics
Pregnancy

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Lunt, C. C., Satin, A., Barth, W. H., & Hankins, G. D. V. (1994). The effect of indomethacin tocolysis on maternal coagulation status. Obstetrics and Gynecology, 84(5), 820-822.

The effect of indomethacin tocolysis on maternal coagulation status. / Lunt, Chad C.; Satin, Andrew; Barth, William H.; Hankins, Gary D V.

In: Obstetrics and Gynecology, Vol. 84, No. 5, 1994, p. 820-822.

Research output: Contribution to journalArticle

Lunt, CC, Satin, A, Barth, WH & Hankins, GDV 1994, 'The effect of indomethacin tocolysis on maternal coagulation status', Obstetrics and Gynecology, vol. 84, no. 5, pp. 820-822.
Lunt, Chad C. ; Satin, Andrew ; Barth, William H. ; Hankins, Gary D V. / The effect of indomethacin tocolysis on maternal coagulation status. In: Obstetrics and Gynecology. 1994 ; Vol. 84, No. 5. pp. 820-822.
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