Intraocular pressure fell logarithmically with decline in rectal temperature during immersion hypothermia in rabbits. The first significant fall appeared at 33 °C. and the pressure was halved for every 20.5 °C. fall in body temperature thereafter. The temperature coefficient (Q10) of this process was found to be 1.4. A decrease in the facility of outflow occurred during hypothermia as demonstrated by tonography and perfusion in vivo and in vitro. However, this fall could be entirely accounted for by the changes in viscosity of water with temperature. Aqueous flow decreased 80 to 90 percent al 19 °C. as estimated by comparative tonometric and tonographic studies of normothermic and hypothermic rabbits. For every 7 °C. fall in body temperature, the flow rate was halved.
|Original language||English (US)|
|Number of pages||9|
|Journal||American journal of ophthalmology|
|Issue number||5 PART 2|
|State||Published - May 1960|
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