The effect of hypothermia on aqueous humor dynamics. I. Intraocular pressure and outflow facility of the rabbit eye

Irvin P. Pollack, Bernard Becker, Marguerite A. Constant

Research output: Contribution to journalArticle

Abstract

Intraocular pressure fell logarithmically with decline in rectal temperature during immersion hypothermia in rabbits. The first significant fall appeared at 33 °C. and the pressure was halved for every 20.5 °C. fall in body temperature thereafter. The temperature coefficient (Q10) of this process was found to be 1.4. A decrease in the facility of outflow occurred during hypothermia as demonstrated by tonography and perfusion in vivo and in vitro. However, this fall could be entirely accounted for by the changes in viscosity of water with temperature. Aqueous flow decreased 80 to 90 percent al 19 °C. as estimated by comparative tonometric and tonographic studies of normothermic and hypothermic rabbits. For every 7 °C. fall in body temperature, the flow rate was halved.

Original languageEnglish (US)
Pages (from-to)1126-1134
Number of pages9
JournalAmerican Journal of Ophthalmology
Volume49
Issue number5 PART 2
StatePublished - May 1960
Externally publishedYes

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Aqueous Humor
Hypothermia
Intraocular Pressure
Rabbits
Body Temperature
Temperature
Immersion
Viscosity
Perfusion
Pressure
Water

ASJC Scopus subject areas

  • Ophthalmology

Cite this

The effect of hypothermia on aqueous humor dynamics. I. Intraocular pressure and outflow facility of the rabbit eye. / Pollack, Irvin P.; Becker, Bernard; Constant, Marguerite A.

In: American Journal of Ophthalmology, Vol. 49, No. 5 PART 2, 05.1960, p. 1126-1134.

Research output: Contribution to journalArticle

Pollack, Irvin P. ; Becker, Bernard ; Constant, Marguerite A. / The effect of hypothermia on aqueous humor dynamics. I. Intraocular pressure and outflow facility of the rabbit eye. In: American Journal of Ophthalmology. 1960 ; Vol. 49, No. 5 PART 2. pp. 1126-1134.
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