The effect of hydroxyurea on hemoglobin F in patients with myeloproliferative syndromes

B. P. Alter, H. S. Gilbert

Research output: Contribution to journalArticle

Abstract

Fetal hemoglobin (Hb F) may increase in patients receiving chemotherapeutic drugs, a result of potential use in patients with symptomatic hemoglobinopathies. We examined Hb F in 13 patients with myeloproliferative disease (six polycythemia vera, five polycythemia vera with myeloid metaplasia, one agnogenic myeloid metaplasia, and one chronic myelogenous leukemia) who were treated with hydroxyurea. Four patients showed an increased in Hb F from 8% while on hydroxyurea, and a decline to

Original languageEnglish (US)
Pages (from-to)373-379
Number of pages7
JournalBlood
Volume66
Issue number2
StatePublished - 1985
Externally publishedYes

Fingerprint

Fetal Hemoglobin
Hydroxyurea
Polycythemia Vera
Primary Myelofibrosis
Hemoglobinopathies
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Hematology

Cite this

The effect of hydroxyurea on hemoglobin F in patients with myeloproliferative syndromes. / Alter, B. P.; Gilbert, H. S.

In: Blood, Vol. 66, No. 2, 1985, p. 373-379.

Research output: Contribution to journalArticle

Alter, BP & Gilbert, HS 1985, 'The effect of hydroxyurea on hemoglobin F in patients with myeloproliferative syndromes', Blood, vol. 66, no. 2, pp. 373-379.
Alter, B. P. ; Gilbert, H. S. / The effect of hydroxyurea on hemoglobin F in patients with myeloproliferative syndromes. In: Blood. 1985 ; Vol. 66, No. 2. pp. 373-379.
@article{536480ed9c674b1db09e3a2791014ada,
title = "The effect of hydroxyurea on hemoglobin F in patients with myeloproliferative syndromes",
abstract = "Fetal hemoglobin (Hb F) may increase in patients receiving chemotherapeutic drugs, a result of potential use in patients with symptomatic hemoglobinopathies. We examined Hb F in 13 patients with myeloproliferative disease (six polycythemia vera, five polycythemia vera with myeloid metaplasia, one agnogenic myeloid metaplasia, and one chronic myelogenous leukemia) who were treated with hydroxyurea. Four patients showed an increased in Hb F from 8{\%} while on hydroxyurea, and a decline to",
author = "Alter, {B. P.} and Gilbert, {H. S.}",
year = "1985",
language = "English (US)",
volume = "66",
pages = "373--379",
journal = "Blood",
issn = "0006-4971",
publisher = "American Society of Hematology",
number = "2",

}

TY - JOUR

T1 - The effect of hydroxyurea on hemoglobin F in patients with myeloproliferative syndromes

AU - Alter, B. P.

AU - Gilbert, H. S.

PY - 1985

Y1 - 1985

N2 - Fetal hemoglobin (Hb F) may increase in patients receiving chemotherapeutic drugs, a result of potential use in patients with symptomatic hemoglobinopathies. We examined Hb F in 13 patients with myeloproliferative disease (six polycythemia vera, five polycythemia vera with myeloid metaplasia, one agnogenic myeloid metaplasia, and one chronic myelogenous leukemia) who were treated with hydroxyurea. Four patients showed an increased in Hb F from 8% while on hydroxyurea, and a decline to

AB - Fetal hemoglobin (Hb F) may increase in patients receiving chemotherapeutic drugs, a result of potential use in patients with symptomatic hemoglobinopathies. We examined Hb F in 13 patients with myeloproliferative disease (six polycythemia vera, five polycythemia vera with myeloid metaplasia, one agnogenic myeloid metaplasia, and one chronic myelogenous leukemia) who were treated with hydroxyurea. Four patients showed an increased in Hb F from 8% while on hydroxyurea, and a decline to

UR - http://www.scopus.com/inward/record.url?scp=0021853293&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021853293&partnerID=8YFLogxK

M3 - Article

C2 - 2410068

AN - SCOPUS:0021853293

VL - 66

SP - 373

EP - 379

JO - Blood

JF - Blood

SN - 0006-4971

IS - 2

ER -