The effect of hydroxyurea on hemoglobin F in patients with myeloproliferative syndromes

B. P. Alter, H. S. Gilbert

Research output: Contribution to journalArticlepeer-review

Abstract

Fetal hemoglobin (Hb F) may increase in patients receiving chemotherapeutic drugs, a result of potential use in patients with symptomatic hemoglobinopathies. We examined Hb F in 13 patients with myeloproliferative disease (six polycythemia vera, five polycythemia vera with myeloid metaplasia, one agnogenic myeloid metaplasia, and one chronic myelogenous leukemia) who were treated with hydroxyurea. Four patients showed an increased in Hb F from 8% while on hydroxyurea, and a decline to

Original languageEnglish (US)
Pages (from-to)373-379
Number of pages7
JournalBlood
Volume66
Issue number2
StatePublished - 1985
Externally publishedYes

ASJC Scopus subject areas

  • Hematology

Fingerprint Dive into the research topics of 'The effect of hydroxyurea on hemoglobin F in patients with myeloproliferative syndromes'. Together they form a unique fingerprint.

Cite this