In this study, administration of hydrocortisone to fetal lambs was associated with an increase in lung volume, but alterations in fetal lung surfactant (as measured by alveolar stability, lung extract surface tensions and phosphatidylcholine concentrations) were not discerned. Our findings support recent rhesus monkey studies suggesting that the principal effect of glucocorticoids is upon nonsurfactant components of the lung.
|Original language||English (US)|
|Number of pages||8|
|Journal||Journal of Reproductive Medicine for the Obstetrician and Gynecologist|
|State||Published - 1981|
ASJC Scopus subject areas
- Reproductive Medicine
- Obstetrics and Gynecology