The Effect of Highly Active Antiretroviral Therapy on Dermatologic Disease in a Longitudinal Study of HIV Type 1-Infected Women

Toby Maurer, Lori K E Rodrigues, Niloufar Ameli, Nittaya Phanuphak, Stephen J Gange, Jack DeHovitz, Audrey L. French, Marshall Glesby, Carol Jordan, Ann Khalsa, Nancy A. Hessol

Research output: Contribution to journalArticle

Abstract

The effect of highly active antiretroviral therapy (HAART) on skin diseases was evaluated in 878 human immunodeficiency virus type 1 (HIV-1)-infected women in the Women's Interagency HIV Study, a multicenter prospective study. HIV-1-infected women receiving HAART were less likely to have eczema, folliculitis, tinea pedis, and xerosis than were women who had not initiated HAART, independent of CD4+ cell count. Participants who had a prior history of a nadir CD4+ cell count of + cell counts of 200-349 cells/μL were more likely to have eczema and xerosis than were women with a nadir CD4+ cell count of >200 cells/μL and recent CD4+ cell counts of >349 cells/μL. An HIV-1 RNA load of >100,000 copies/mL was associated with increased prevalence of herpes zoster infection (odds ratio, 6.10; 95% confidence interval, 2.00-18.65). History of injection drug use was associated with a higher prevalence of onychomycosis, tinea pedis, and xerosis. Molluscum contagiosum was more prevalent among younger women.

Original languageEnglish (US)
Pages (from-to)579-584
Number of pages6
JournalClinical Infectious Diseases
Volume38
Issue number4
DOIs
StatePublished - Feb 15 2004

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Highly Active Antiretroviral Therapy
Longitudinal Studies
HIV-1
CD4 Lymphocyte Count
Tinea Pedis
Eczema
Molluscum Contagiosum
Folliculitis
Onychomycosis
Herpes Zoster
Skin Diseases
Multicenter Studies
Cell Count
Odds Ratio
HIV
Prospective Studies
RNA
Confidence Intervals
Injections
Infection

ASJC Scopus subject areas

  • Immunology

Cite this

The Effect of Highly Active Antiretroviral Therapy on Dermatologic Disease in a Longitudinal Study of HIV Type 1-Infected Women. / Maurer, Toby; Rodrigues, Lori K E; Ameli, Niloufar; Phanuphak, Nittaya; Gange, Stephen J; DeHovitz, Jack; French, Audrey L.; Glesby, Marshall; Jordan, Carol; Khalsa, Ann; Hessol, Nancy A.

In: Clinical Infectious Diseases, Vol. 38, No. 4, 15.02.2004, p. 579-584.

Research output: Contribution to journalArticle

Maurer, T, Rodrigues, LKE, Ameli, N, Phanuphak, N, Gange, SJ, DeHovitz, J, French, AL, Glesby, M, Jordan, C, Khalsa, A & Hessol, NA 2004, 'The Effect of Highly Active Antiretroviral Therapy on Dermatologic Disease in a Longitudinal Study of HIV Type 1-Infected Women', Clinical Infectious Diseases, vol. 38, no. 4, pp. 579-584. https://doi.org/10.1086/381264
Maurer, Toby ; Rodrigues, Lori K E ; Ameli, Niloufar ; Phanuphak, Nittaya ; Gange, Stephen J ; DeHovitz, Jack ; French, Audrey L. ; Glesby, Marshall ; Jordan, Carol ; Khalsa, Ann ; Hessol, Nancy A. / The Effect of Highly Active Antiretroviral Therapy on Dermatologic Disease in a Longitudinal Study of HIV Type 1-Infected Women. In: Clinical Infectious Diseases. 2004 ; Vol. 38, No. 4. pp. 579-584.
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