The effect of gestational parity on FEV1 in a group of healthy volunteer women

R. Harik-Khan, Robert A Wise, C. Lou, C. H. Morrell, L. J. Brant, J. L. Fozard

Research output: Contribution to journalArticle

Abstract

In the past, studies utilizing within-subject comparisons of small groups of pregnant women showed that forced expiratory volume in 1 s (FEV1) remained essentially unchanged during pregnancy. However, one of the findings from an epidemiological study was that women with greater number of children experienced a faster decline of FEV1. The aim of this study was to examine the effect of parity on FEV1 in a group of healthy volunteer women. To this end, cross-sectional multiple regression analyses of data from 397 healthy women participants in the Baltimore Longitudinal Study of Aging (BLSA) with a mean (range) age of 47.7 (18-92) years were performed. Similar analyses were done using the younger (50 years or less) and the older (> 50 years) subgroups. After controlling for age, height, weight, and smoking, parity as a dichotomous variable was associated with a higher FEV1 in women of child-bearing age (0.139 l; P = 0.02) but not in the older women. There was a modest link with the number of children (P = 0.05), with the first child possibly having the greatest effect on FEV1. We could not account for the effect of parity on FEV1 by the educational level, occupation, health status of the women, or by the presence of a cohort effect. Thus the nulliparous state is associated with lower FEV1 in this group of healthy adult women of child-bearing age.

Original languageEnglish (US)
Pages (from-to)382-388
Number of pages7
JournalRespiratory Medicine
Volume93
Issue number6
DOIs
StatePublished - Jun 1999

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Forced Expiratory Volume
Parity
Healthy Volunteers
Health Status
Cohort Effect
Baltimore
Occupations
Longitudinal Studies
Pregnant Women
Epidemiologic Studies
Smoking
Regression Analysis
Weights and Measures
Pregnancy

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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The effect of gestational parity on FEV1 in a group of healthy volunteer women. / Harik-Khan, R.; Wise, Robert A; Lou, C.; Morrell, C. H.; Brant, L. J.; Fozard, J. L.

In: Respiratory Medicine, Vol. 93, No. 6, 06.1999, p. 382-388.

Research output: Contribution to journalArticle

Harik-Khan, R, Wise, RA, Lou, C, Morrell, CH, Brant, LJ & Fozard, JL 1999, 'The effect of gestational parity on FEV1 in a group of healthy volunteer women', Respiratory Medicine, vol. 93, no. 6, pp. 382-388. https://doi.org/10.1053/rmed.1999.0572
Harik-Khan, R. ; Wise, Robert A ; Lou, C. ; Morrell, C. H. ; Brant, L. J. ; Fozard, J. L. / The effect of gestational parity on FEV1 in a group of healthy volunteer women. In: Respiratory Medicine. 1999 ; Vol. 93, No. 6. pp. 382-388.
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