The effect of diphenylhydantoin on basal and stimulated thyroid stimulating hormone (TSH) and prolactin secretion in euthyroid and hypothyroid rats

S. R. Gambert, T. L. Garthwaite

Research output: Contribution to journalArticle

Abstract

The data suggest that in hypothyroidism DPH is capable of increasing basal levels of TSH and prolactin. Although stimulated levels of these hormones are similar, the proportionate changes are blunted in the DPH treated group. Dilantin does not affect these hormones in euthyroid animals. The mechanism by which hypothyroidism interacts with DPH to effect these changes is unknown.

Original languageEnglish (US)
Pages (from-to)636-637
Number of pages2
JournalHormone and Metabolic Research
Volume12
Issue number11
DOIs
StatePublished - Jan 1 1980

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Biochemistry
  • Endocrinology
  • Clinical Biochemistry
  • Biochemistry, medical

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