The effect of community socioeconomic status on sepsis-attributable mortality

Panagis Galiatsatos, Emily P. Brigham, Juliana Pietri, Kathleen Littleton, Seungyoung Hwang, Michael C. Grant, Nadia N. Hansel, Edward S. Chen

Research output: Contribution to journalArticlepeer-review


Purpose: Community factors may play a role in determining individual risk for sepsis, as well as sepsis-related morbidity and mortality. We sought to define the relationship between community socioeconomic status and mortality due to sepsis in an urban locale. Methods: Using community statistical areas of Baltimore City, we dichotomized neighborhoods at median household income, and compared distribution of outcomes of interest within the two income categories. We performed multivariable regression analyses to determine the relationship between socioeconomic variables and sepsis-attributable mortality. Results: The collective median household income was $38,660 (IQR $32,530, 54,480), family poverty rate was 28.4% (IQR 13.5, 38.8%), and rate of death from sepsis was 3.1 per 10,000 persons (IQR 2.60, 4.10). Lower household income communities demonstrated higher rates of death from sepsis (3.65 (IQR 2.78, 4.40)) than higher household income communities (2.80 (IQR 2.05, 3.55)) (p =.02). In regression models, household income (β = −8.42, p =.006) and percentage of poverty in communities (β = 2.71, p =.01) demonstrated associations with sepsis-attributable mortality. Discussion: Our findings suggest that socioeconomic variables play significant role in sepsis-attributable mortality. Such confirmation of regional disparities in mortality due to sepsis warrants further consideration, as well as integration, for future national sepsis policies.

Original languageEnglish (US)
Pages (from-to)129-133
Number of pages5
JournalJournal of Critical Care
StatePublished - Aug 2018


  • Community
  • Health disparities
  • Poverty
  • Sepsis

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine


Dive into the research topics of 'The effect of community socioeconomic status on sepsis-attributable mortality'. Together they form a unique fingerprint.

Cite this