The effect of allogeneic lymphocytes on the isolated perfused kidney

Bjarne K.H. Semb, G. Melville Williams, David H. Hume

Research output: Contribution to journalArticle

Abstract

The hemodynamic effects of unsensitized small lymphocytes were studied, during simultaneous ex vivo perfusion of allogeneic and isogeneic rat kidneys. It was demonstrated that lymphocytes produced a greater increase in vascular resistance in the allogeneic kidney, and that more cells were retained in the allogeneic than in the isogeneic kidney. The effects were interpreted as allogeneic adsorption between cells of different genotypes.

Original languageEnglish (US)
Pages (from-to)977-985
Number of pages9
JournalTransplantation
Volume6
Issue number9
DOIs
StatePublished - Dec 1968

ASJC Scopus subject areas

  • Transplantation

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