The effect of age on the in vitro metabolism of androgen by guinea pig testis

Charles A. Snipes, W. Gary Becker, C. J. Migeon

Research output: Contribution to journalArticlepeer-review

Abstract

Progesterone-4-C14 was incubated with minces of testes from Guinea pigs of different ages. Progesterone-C14 disappearance and 17α-hydroxyprogesterone-C14 appearance did not change consistently with age. However, more androstenedione-C14 and less testosterone-C14 appeared in tissue from younger animals. It is concluded that androstenedione is reduced less readily in younger animals.

Original languageEnglish (US)
Pages (from-to)771-776
Number of pages6
JournalSteroids
Volume6
Issue number6
DOIs
StatePublished - Dec 1965

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Endocrinology
  • Pharmacology
  • Clinical Biochemistry
  • Organic Chemistry

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