The effect of active and passive household cigarette smoke exposure on pregnant women with asthma

Roger B. Newman, Valerija Momirova, Mitchell P. Dombrowski, Michael Schatz, Robert A Wise, Mark Landon, Dwight J. Rouse, Marshall Lindheimer, Steve N. Caritis, Jeanne Sheffield, Menachem Miodovnik, Ronald J. Wapner, Michael W. Varner, Mary Jo O'Sullivan, Deborah L. Conway

Research output: Contribution to journalArticle

Abstract

Background: The article was designed to estimate the effect of active and passive household cigarette smoke exposure on asthma severity and obstetric and neonatal outcomes in pregnant women with asthma. Methods: We used a secondary observational analysis of pregnant women with mild and moderate-severe asthma enrolled in a prospective observational cohort study of asthma in pregnancy and a randomized clinical trial (RCT) comparing inhaled beclomethasone and oral theophylline. A baseline questionnaire detailing smoking history and passive household smoke exposure was given to each patient. Smoking status was confirmed in the RCT using cotinine levels. Data on asthma severity and obstetric and neonatal outcomes were collected and analyzed with respect to self-reported tobacco smoke exposure. Kruskal-Wallis and Pearson χ2 statistics were used to test for significance. Results: A total of 2,210 women were enrolled: 1,812 in the observational study and 398 in the RCT. Four hundred and eight (18%) women reported current active smoking. Of the nonsmokers, 790 (36%) women reported passive household smoke exposure. Active smoking was associated with more total symptomatic days (P

Original languageEnglish (US)
Pages (from-to)601-608
Number of pages8
JournalChest
Volume137
Issue number3
DOIs
StatePublished - Mar 1 2010

Fingerprint

Smoke
Tobacco Products
Pregnant Women
Asthma
Randomized Controlled Trials
Smoking
Obstetrics
Observational Studies
Beclomethasone
Cotinine
Tobacco Smoke Pollution
Theophylline
Tobacco
Cohort Studies
History
Pregnancy

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine
  • Cardiology and Cardiovascular Medicine

Cite this

Newman, R. B., Momirova, V., Dombrowski, M. P., Schatz, M., Wise, R. A., Landon, M., ... Conway, D. L. (2010). The effect of active and passive household cigarette smoke exposure on pregnant women with asthma. Chest, 137(3), 601-608. https://doi.org/10.1378/chest.09-0942

The effect of active and passive household cigarette smoke exposure on pregnant women with asthma. / Newman, Roger B.; Momirova, Valerija; Dombrowski, Mitchell P.; Schatz, Michael; Wise, Robert A; Landon, Mark; Rouse, Dwight J.; Lindheimer, Marshall; Caritis, Steve N.; Sheffield, Jeanne; Miodovnik, Menachem; Wapner, Ronald J.; Varner, Michael W.; O'Sullivan, Mary Jo; Conway, Deborah L.

In: Chest, Vol. 137, No. 3, 01.03.2010, p. 601-608.

Research output: Contribution to journalArticle

Newman, RB, Momirova, V, Dombrowski, MP, Schatz, M, Wise, RA, Landon, M, Rouse, DJ, Lindheimer, M, Caritis, SN, Sheffield, J, Miodovnik, M, Wapner, RJ, Varner, MW, O'Sullivan, MJ & Conway, DL 2010, 'The effect of active and passive household cigarette smoke exposure on pregnant women with asthma', Chest, vol. 137, no. 3, pp. 601-608. https://doi.org/10.1378/chest.09-0942
Newman, Roger B. ; Momirova, Valerija ; Dombrowski, Mitchell P. ; Schatz, Michael ; Wise, Robert A ; Landon, Mark ; Rouse, Dwight J. ; Lindheimer, Marshall ; Caritis, Steve N. ; Sheffield, Jeanne ; Miodovnik, Menachem ; Wapner, Ronald J. ; Varner, Michael W. ; O'Sullivan, Mary Jo ; Conway, Deborah L. / The effect of active and passive household cigarette smoke exposure on pregnant women with asthma. In: Chest. 2010 ; Vol. 137, No. 3. pp. 601-608.
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