TY - JOUR
T1 - The dysarthria—clumsy hand syndrome
T2 - A distinct clinical entity related to pontine infarction
AU - Glass, Jonathan D.
AU - Levey, Allan I.
AU - Rothstein, Jeffrey D.
PY - 1990/5
Y1 - 1990/5
N2 - Using magnetic resonance imaging, we studied 6 patients with the dysarthria–clumsy hand syndrome. All were found to have pontine infarctions contralateral to the symptomatic side. Clinically, these patients exhibited dysarthria; “clumsiness,” characterized by dysmetria, dysrhythmia, dysdiadochokinesia and sometimes truncal and gait ataxia; and mild ipsilateral weakness. Previous clinical‐anatomical correlations for this syndrome are limited by inconsistencies in clinical diagnostic criteria and low‐resolution imaging methods. In our patients, and in a review of the literature, the overwhelming majority of patients with the dysarthria–clumsy hand syndrome had pontine infarcts. We conclude that if rigid clinical criteria are used, the label of the dysarthria–clumsy hand syndrome predicts a lesion in the contralateral basis pontis.
AB - Using magnetic resonance imaging, we studied 6 patients with the dysarthria–clumsy hand syndrome. All were found to have pontine infarctions contralateral to the symptomatic side. Clinically, these patients exhibited dysarthria; “clumsiness,” characterized by dysmetria, dysrhythmia, dysdiadochokinesia and sometimes truncal and gait ataxia; and mild ipsilateral weakness. Previous clinical‐anatomical correlations for this syndrome are limited by inconsistencies in clinical diagnostic criteria and low‐resolution imaging methods. In our patients, and in a review of the literature, the overwhelming majority of patients with the dysarthria–clumsy hand syndrome had pontine infarcts. We conclude that if rigid clinical criteria are used, the label of the dysarthria–clumsy hand syndrome predicts a lesion in the contralateral basis pontis.
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U2 - 10.1002/ana.410270506
DO - 10.1002/ana.410270506
M3 - Article
C2 - 2360789
AN - SCOPUS:0025274772
VL - 27
SP - 487
EP - 494
JO - Annals of Neurology
JF - Annals of Neurology
SN - 0364-5134
IS - 5
ER -