The Diagnosis of Leydig Cell Tumors in Childhood

Maria D. Urban, Peter A. Lee, Leslie P. Plotnick, Claude J. Migeon

Research output: Contribution to journalArticle

Abstract

We report the clinical and hormonal findings in two boys with isosexual precocity secondary to Leydig cell tumor of the testis. The hormonal profile at the initial evaluation was quite different in the two cases suggesting differences in steroid biosynthesis by the tumors. These differences indicate that a dexamethasone suppression test may be required to differentiate between Leydig cell tumors and congenital virilizing adrenal hyperplasia with adrenal rest tissue located within the testes.

Original languageEnglish (US)
Pages (from-to)494-497
Number of pages4
JournalAmerican Journal of Diseases of Children
Volume132
Issue number5
DOIs
StatePublished - 1978

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Leydig Cell Tumor
Testis
Congenital Adrenal Hyperplasia
Dexamethasone
Steroids
Neoplasms

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

The Diagnosis of Leydig Cell Tumors in Childhood. / Urban, Maria D.; Lee, Peter A.; Plotnick, Leslie P.; Migeon, Claude J.

In: American Journal of Diseases of Children, Vol. 132, No. 5, 1978, p. 494-497.

Research output: Contribution to journalArticle

Urban, Maria D. ; Lee, Peter A. ; Plotnick, Leslie P. ; Migeon, Claude J. / The Diagnosis of Leydig Cell Tumors in Childhood. In: American Journal of Diseases of Children. 1978 ; Vol. 132, No. 5. pp. 494-497.
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