The diagnosis and treatment of secondary glaucoma after hyphema in sickle cell patients

Research output: Contribution to journalArticle

Abstract

Four patients with sickle cell hemoglobinopathies (one sickle cell hemoglobin C disease (SC); three sickle cell trait (AS)) and hyphemas had a higher percentage of erythrocytes sickled in their anterior chambers than in their circulating venous blood. Intraocular pressure (IOP) was severely increased, despite relatively small amounts of intracameral blood. Systemic hypotensive agents were not always successful in reducing IOP, and in patients with sickle cell hemoglobinopathy, are probably contraindicated in high or repeated dose regimens. Moderate increase of IOP in sickle cell hemoglobinopathy patients may produced rapid deterioration of visual function, because of a greater than usual effect on vascular perfusion in the central retinal artery and optic nerve. Early anterior chamber paracentesis may be the best treatment for this type of hyphemainduced secondary glaucoma.

Original languageEnglish (US)
Pages (from-to)43-49
Number of pages7
JournalAmerican Journal of Ophthalmology
Volume87
Issue number1
StatePublished - 1979
Externally publishedYes

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Hyphema
Hemoglobinopathies
Intraocular Pressure
Glaucoma
Anterior Chamber
Hemoglobin SC Disease
Sickle Cell Trait
Retinal Artery
Paracentesis
Optic Nerve
Blood Vessels
Therapeutics
Perfusion
Erythrocytes

ASJC Scopus subject areas

  • Ophthalmology

Cite this

The diagnosis and treatment of secondary glaucoma after hyphema in sickle cell patients. / Goldberg, Morton F.

In: American Journal of Ophthalmology, Vol. 87, No. 1, 1979, p. 43-49.

Research output: Contribution to journalArticle

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