The Dexamethasone Suppression Test in Patients with Presenile and Senile Dementia of the Alzheimer's Type

MICHAEL A. JENIKE, MARILYN S. ALBERT

Research output: Contribution to journalArticle

Abstract

The dexamethasone suppression test (DST) was performed on 18 patients with presenile and senile dementia of the Alzheimer's type. Objective cognitive testing showed that 13 patients were mildly to moderately impaired and five were moderately to severely impaired. The Hamilton Depression Scale yielded normal results in all patients. The DST results were abnormal in only one of the mildly impaired patients but in four of the five moderately impaired patients. These data suggest that the DST may be a useful clinical tool in mildly impaired patients with Alzheimer's disease but is likely to be confounded by disease in moderately to severely impaired patients. 1984 The American Geriatrics Society

Original languageEnglish (US)
Pages (from-to)441-444
Number of pages4
JournalJournal of the American Geriatrics Society
Volume32
Issue number6
DOIs
StatePublished - Jun 1984
Externally publishedYes

ASJC Scopus subject areas

  • Geriatrics and Gerontology

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