The determination of serotonin (5-hydroxytryptamine) in human blood

T. Phillip Waalkes

Research output: Contribution to journalArticle

Abstract

A sensitive fluorometric method for serotonin assay in human whole blood (and plasma) has been described. After precipitation of the blood proteins, serotonin is extracted from a basic solution into organic solvents and is purified and concentrated by means of an ion exchange medium, cotton acid succinate, or by extraction into acid. The values for blood from 21 patients are given and discussed.

Original languageEnglish (US)
Pages (from-to)824-829
Number of pages6
JournalThe Journal of Laboratory and Clinical Medicine
Volume53
Issue number5
StatePublished - May 1959
Externally publishedYes

Fingerprint

Serotonin
Blood
Acids
Ion Exchange
Succinic Acid
Organic solvents
Cotton
Blood Proteins
Assays
Ion exchange
Plasmas

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medicine(all)

Cite this

The determination of serotonin (5-hydroxytryptamine) in human blood. / Waalkes, T. Phillip.

In: The Journal of Laboratory and Clinical Medicine, Vol. 53, No. 5, 05.1959, p. 824-829.

Research output: Contribution to journalArticle

@article{f271417150364c6d9071846203b0d19f,
title = "The determination of serotonin (5-hydroxytryptamine) in human blood",
abstract = "A sensitive fluorometric method for serotonin assay in human whole blood (and plasma) has been described. After precipitation of the blood proteins, serotonin is extracted from a basic solution into organic solvents and is purified and concentrated by means of an ion exchange medium, cotton acid succinate, or by extraction into acid. The values for blood from 21 patients are given and discussed.",
author = "Waalkes, {T. Phillip}",
year = "1959",
month = "5",
language = "English (US)",
volume = "53",
pages = "824--829",
journal = "Translational Research",
issn = "1931-5244",
publisher = "Mosby Inc.",
number = "5",

}

TY - JOUR

T1 - The determination of serotonin (5-hydroxytryptamine) in human blood

AU - Waalkes, T. Phillip

PY - 1959/5

Y1 - 1959/5

N2 - A sensitive fluorometric method for serotonin assay in human whole blood (and plasma) has been described. After precipitation of the blood proteins, serotonin is extracted from a basic solution into organic solvents and is purified and concentrated by means of an ion exchange medium, cotton acid succinate, or by extraction into acid. The values for blood from 21 patients are given and discussed.

AB - A sensitive fluorometric method for serotonin assay in human whole blood (and plasma) has been described. After precipitation of the blood proteins, serotonin is extracted from a basic solution into organic solvents and is purified and concentrated by means of an ion exchange medium, cotton acid succinate, or by extraction into acid. The values for blood from 21 patients are given and discussed.

UR - http://www.scopus.com/inward/record.url?scp=0042652722&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0042652722&partnerID=8YFLogxK

M3 - Article

VL - 53

SP - 824

EP - 829

JO - Translational Research

JF - Translational Research

SN - 1931-5244

IS - 5

ER -